Immunity, Cellular Clinical Trial
NCT number | NCT00241657 |
Other study ID # | KPS10 |
Secondary ID | |
Status | Completed |
Phase | Phase 2 |
First received | October 17, 2005 |
Last updated | December 14, 2005 |
BCG vaccination has been found to provide greater protection against TB in the UK than in Malawi. This study compares immune responses in BCG-vaccinated and unvaccinated teenagers and young adults in Malawi and in the UK.
Status | Completed |
Enrollment | 0 |
Est. completion date | |
Est. primary completion date | |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | Both |
Age group | 12 Years to 25 Years |
Eligibility |
Inclusion Criteria: - BCG unvaccinated - HIV negative - Not pregnant - Informed Consent Exclusion Criteria: - HIV positive - Pregnant - Seriously ill |
Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Single Blind, Primary Purpose: Prevention
Country | Name | City | State |
---|---|---|---|
Malawi | Karonga Prevention Study | Chilumba | Karonga District |
United Kingdom | Redbridge and Waltham Forest Primary Care Trust | Ilford | Essex |
Lead Sponsor | Collaborator |
---|---|
London School of Hygiene and Tropical Medicine |
Malawi, United Kingdom,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Delayed-type hypersensitivity | |||
Primary | cytokine responses (eg IFNg) to mycobacterial antigens | |||
Secondary | scar size |
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
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