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The Combination of Teriflunomide and Danazol for Steroid-resistant/Relapse Immune Thrombocytopenia

Immune Thrombocytopenia Clinical Trial

Official title:
A Multicenter, Open-label, Randomized, Controlled, Phase 2 Trial Comparing the Efficacy and Safety of Teriflunomide Plus Danazol in Patients With Steroid-resistant/Relapse ITP

Clinical Trial Summary

To compare the efficacy and safety of teriflunomide plus danazol versus danazol in patients with steroid-resistant/relapse ITP

Clinical Trial Description

This is a prospective, multicenter, randomized, controlled trial of 124 adult patients with steroid-resistant/relapse ITP in China. Patients were randomized to receive either experimental teriflunomide plus danazol or active comparator danazol monotherapy. Treatment was discontinued if very severe or life-threatening adverse events developed or at the patient's request. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06176911
Study type Interventional
Source Peking University People's Hospital
Contact Xiao-Hui Zhang, MD
Phone +8613522338836
Email zhangxh100@sina.com
Status Recruiting
Phase Phase 2
Start date December 5, 2023
Completion date July 15, 2025
View Details
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