The Study of Different Dose Rituximab in the Treatment of ITP

Status Completed

Clinical Trial Summary

The project was undertaking by Qilu Hospital of Shandong University in China. In order to compare the efficacy, safety and response duration of different dose of rituximab in patients primary immune thrombocytopenia(pITP).

Clinical Trial Description

62 patients with pITP who had failed to respond to glucocorticosteroids were randomly divided into 2 groups: group A(n = 32) and group B(n = 30). In group A, Rituximab was given with a fixed dose of 100 mg administered as an intravenous infusion weekly (on day 1, 8, 15 and 22). In group B, Rituximab was given with a single dose of 375mg/m2. The clinical effect, onset time, duration of efficacy and adverse reactions were observed to compare the efficacy and safety of two different plans. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03258866
Study type	Interventional
Source	Shandong University
Contact
Status	Completed
Phase	Phase 4
Start date	January 1, 2010
Completion date	December 31, 2016

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