H. Pylori Eradication for Moderate ITP

Status Recruiting

Clinical Trial Summary

The purpose of this study is to determine the efficacy of H. pylori eradication for the treatment of chronic or persistent immune thrombocytopenic purpura (ITP) patients with moderate thrombocytopenia. This is a multi-center, open label, prospective randomized phase IIl study.

Clinical Trial Description

Current treatment guideline of ITP recommends corticosteroid as the first line treatment when patient has active bleeding or less than 30×10^9/L of platelet, because of side effect and cost issues. Since the first case report by Italian study, several investigators have reported that secondary immune thrombocytopenia (ITP) can occur in patients with Helicobacter pylori (H. pylori) infection. We already reported the efficacy of H. pylori eradication in moderate ITP patients with phase II study (Annals Hematology 2015:94:739-46). To improve the evidence of this strategy for the treatment of moderate ITP, we plan to start this multi-center, open label, prospective randomized phase 3 study. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03177629
Study type	Interventional
Source	Seoul National University Hospital
Contact	Soo-Me Bang, M.D.
Phone	82 31 787 7039
Email	smbang7@snu.ac.kr
Status	Recruiting
Phase	Phase 3
Start date	May 23, 2017
Completion date	December 2020

View Details

See also
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