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Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT04795102
Other study ID # KD/03/20
Secondary ID
Status Completed
Phase N/A
First received
Last updated
Start date January 1, 2020
Est. completion date April 2, 2021

Study information

Verified date September 2021
Source Kafrelsheikh University
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

Immediate implant placement into fresh extraction sockets is gaining popularity because of fewer clinical procedures and maintenance of bone architecture compared to conventional methods, thus reducing the treatment time and increasing patient satisfaction. In addition, the survival rate of the immediate implantation is comparable to that of the healed implantation sites. Recently, ATBG made from compromised teeth was applied in bone defects and resulted in a good clinical efficacy. Moreover, it is more accepted by patients to use extracted teeth as a bone graft material, especially in the case of immediate implant placement. In 2020, Kizildağ and coworkers studied the outcome of PRF as an adjunct with ATBG on bone healing in rabbit peri-implant osseous defects. They reported that combination of ATBG with PRF contributed to significantly higher new bone formation and better bone/implant contact in rabbits with peri-implant bone defects. The main hypothesis behind this study is that using L-PRF with ATBG following immediate implant placement could promote stabilization of graft particles and enhance new bone formation with a shorter time. Therefore, the purpose of this study was to compare the clinical and radiographic outcomes of ATBG on bone formation with or without L-PRF around immediately placed dental implants in periodontally compromised teeth.


Recruitment information / eligibility

Status Completed
Enrollment 26
Est. completion date April 2, 2021
Est. primary completion date April 2, 2021
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 18 Years to 50 Years
Eligibility Inclusion Criteria: - Teeth need to be extracted for periodontal reasons with a defect of labial bone (horizontal or vertical bone defect). - the teeth without acute inflammation. - no uncontrolled systemic disease which is not suitable for implantation. - Good systemic and oral health. Exclusion Criteria: - patients with systemic diseases or medications known to alter healing processes - Psychiatric disorders. - Root canal treated teeth. - patients undergoing or who had undergone radiation therapy and chemotherapy to the head and neck region during 12 months. - patients with para-functional habits. - alcoholics. - drug abusers. - heavy smokers

Study Design


Intervention

Combination Product:
immediate implant placement with ATBG and L-PRF
immediate implant placement using ATBG as a graft material, with L-PRF
immediate implant placement with ATBG
immediate implant placement using ATBG as a graft material without L-PRF

Locations

Country Name City State
Egypt Faculty of Dentistry, Kafrelsheikh University Kafr Ash Shaykh

Sponsors (1)

Lead Sponsor Collaborator
Dalia Rasheed Issa

Country where clinical trial is conducted

Egypt, 

Outcome

Type Measure Description Time frame Safety issue
Primary clinical evaluation of bone formation around immediately placed dental implants Changes on bone formation using ATBG with or without L-PRF around immediately placed dental implants in periodontally compromised teeth 9 months
Primary radiographic outcome around immediately placed dental implants the radiographic outcome of ATBG on bone formation with or without L-PRF around immediately placed dental implants in periodontally compromised teeth 9 months
See also
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Completed NCT05990283 - Socket Shield Technique and Guided Bone Regeneration N/A
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Recruiting NCT05436158 - The Use of a New Safe Angle Position for Implant Placement in the Anterior Region.
Not yet recruiting NCT06246253 - Bone Formed Labial to the Implant in Relation to the Horizontal Gap Dimension in Immediate Implant Placement.
Not yet recruiting NCT06207565 - Immediate Implant Placement Utilizing Vestibular Flap Versus Single Flap Approach With Bone Graft N/A
Enrolling by invitation NCT05330702 - Ultrasound-based Imaging to Detect Early Changes of Hard and Soft Tissue Around Immediately Placed Implants With or Without Soft Tissue Augmentation N/A
Enrolling by invitation NCT05880771 - Immediate Implant Placement: a Clinical and Radiographic Study on Hard and Soft Tissues Retraction at One Year. N/A
Completed NCT03422458 - The Impact of Immediate Implant Placement on Alveolar Ridge Preservation Techniques N/A
Completed NCT04803500 - Simvastatin Around Immediate Implant Phase 2