IGA Glomerulonephritis Clinical Trial
Verified date | September 2000 |
Source | Office of Rare Diseases (ORD) |
Contact | n/a |
Is FDA regulated | No |
Health authority | United States: Federal Government |
Study type | Interventional |
OBJECTIVES: I. Determine the most sensitive outcome measures (functional or morphological)
of a progressive renal injury in patients with IgA nephropathy.
II. Determine which of these patients are destined to progress to further injury in order to
target them for therapy.
III. Elucidate the determinants of progression in those patients who exhibit evidence of
either increasing impairment of ultrafiltration capacity or ongoing destruction of nephrons.
Status | Completed |
Enrollment | 43 |
Est. completion date | |
Est. primary completion date | |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | Both |
Age group | 13 Years to 60 Years |
Eligibility |
Histologically confirmed IgA nephropathy, diagnosed within the past 3 years Clinical presentation of either isolated hematuria/proteinuria for less than 3 years OR Acute nephritic or nephrotic syndrome No secondary forms of IgA nephropathy associated with chronic inflammatory disease of the bowel and liver No end stage renal failure as defined by the following: Glomerular filtration rate less than 15 mL/min AND Extensive glomerulosclerosis and tubulointerstitial damage No systemic lupus erythematosus or systemic (extrarenal) vasculitis (Henoch-Schonlein syndrome) Healthy volunteers will be accrued as a control group No other concurrent medical or psychiatric illness that would preclude study |
Primary Purpose: Treatment
Country | Name | City | State |
---|---|---|---|
n/a |
Lead Sponsor | Collaborator |
---|---|
National Center for Research Resources (NCRR) | Stanford University |
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT00004448 -
Alternate Day Prednisone or Daily Fish Oil Supplements in Patients With Immunoglobulin A Nephropathy
|
Phase 2 | |
Completed |
NCT01560052 -
Therapeutic Evaluation of Steroids in IgA Nephropathy Global Study (TESTING Low Dose Study)
|
N/A | |
Completed |
NCT02527902 -
Autonomic Nervous System (ANS) and Renal Function in Immunoglobin A (IgA) Nephropathy
|
N/A | |
Completed |
NCT00004305 -
Study of Genetic Anomalies of Complement Related Proteins in Patients With IgA Glomerulonephritis
|
N/A | |
Completed |
NCT01115426 -
Inhibitors of Angiotensin II in Proteinuric Mesangioproliferative Glomerulonephritis
|
Phase 4 |