Clinical Trials Logo
  1. Home
  2. Hysteroscopy
  3. NCT06172140

Efficacy and Safety of Ciprofol for the Sedation in Patients Undergoing Hysteroscopy

Hysteroscopy Clinical Trial

Official title:
Efficacy and Safety of Ciprofol for the Sedation in Patients Undergoing Hysteroscopy: A Prospective, Randomized, Non-inferiority Trial.

Clinical Trial Summary

Eligible patients undergoing hysteroscopy were randomly assigned in a 1:1 ratio to receive intravenous anesthesia with either propofol (2 mg/kg) or remifentanil (0.4 mg/kg).Continuous monitoring of pulse oximetry (SpO2), blood pressure (BP), heart rate (HR), expired gas partial pressure of carbon dioxide, integrated respiratory index (IPI), tidal volume (TV), respiratory rate (RR), and minute ventilation (MV) was performed.During induction, the MOAA/S score was assessed every 30 seconds. If the MOAA/S score remained >1, a supplementary dose of 1/2 of the initial dose was injected within 10 seconds.If more than 5 supplementary doses were required within 15 minutes, it was considered that the painless hysteroscopy failed and propofol was used to enhance sedation.Continuous oxygen administration at a flow rate of 5 liters per minute was provided through nasal catheters until the patient was fully alert with a MOAA/S score of 5 and vital signs were stable.Observation indicators included: (1) the success rate of hysteroscopy;(2) induction time (MOAA/S ≤ 1 after the first dose);(3) full recovery time of consciousness;(4) operation duration;(5) number of additional anesthetics;(6) incidence of hypotension, hypoxemia, sinus bradycardia, delayed recovery, and injection pain;(7) respiratory parameters and minimum SpO2, IPI values before anesthesia, after induction, and after awakening.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06172140
Study type Interventional
Source Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Contact Ganglan Fu, PhD
Phone 13570275074
Email fugangl@mail.sysu.edu.cn
Status Not yet recruiting
Phase N/A
Start date March 1, 2024
Completion date September 1, 2025
View Details
See also
  Status Clinical Trial Phase
Completed NCT05514236 - Effect of Virtual Reality and Music Therapy on Pain Relief in Outpatient Hysteroscopy N/A
Completed NCT06092541 - Pericervical Analgesia Versus Analesia With Nitrous Oxide (N2O) in Outpatien Operative Hysteroscopy With Miniresector N/A
Not yet recruiting NCT05069077 - the Effect of Music on Pain and Women Satisfaction During Diagnostic Outpatient Hysteroscopy in Postmenopausal Women N/A
Completed NCT03701984 - The Effect of Intrauterine Lidocaine Infusion and Oral Tramadol on Pain During Diagnostic Office Hysteroscopy Phase 4
Not yet recruiting NCT05069025 - Use of Music in Reducing Pain During Outpatient Hysteroscopy in Primarily Infertile Patients N/A
Completed NCT04166500 - Early Outpatient Hysteroscopy Can Prevent Intrauterine Adhesion After Induced Abortion N/A
Not yet recruiting NCT06379841 - Green Hysteroscopy N/A
Completed NCT02863679 - Postoperative Analgesic Efficacy of Tetracaine Hydrochloride Gel N/A
Completed NCT02142686 - Comparison Between Different Filling Pressures in Diagnostic Outpatient Hysteroscopy N/A
Completed NCT02142673 - The Impact of Different Filling Pressures in Operative Outpatient Hysteroscopy on the Procedure Success Rates and Associated Pain. N/A
Completed NCT05540379 - Role of Virtual Reality Simulators in Basic Hysteroscopy Training Competence N/A
Completed NCT04462835 - Feasibility, Effectiveness and Safety of Outpatient Hysteroscopy
Recruiting NCT04862598 - Virtual Reality to Improve Satisfaction in Hysteroscopy Patients N/A
Recruiting NCT01376934 - Clinical Trial of Hysteroscopy in Postmenopausal Women to Compare Techniques N/A
Recruiting NCT03409835 - Effect of Ramosetron on Post-discharge Nausea and Vomiting N/A
Enrolling by invitation NCT03579550 - Hysteroscopic Metroplasty in Unexplained Infertile Women With Dysmorphic Uterus N/A
Recruiting NCT02736071 - Tramadol Versus Celecoxib for Reducing Pain During Operative Office Hysteroscopy Phase 3
Recruiting NCT02736019 - Tramadol Versus Celecoxib for Reducing Pain During Office Hysteroscopy in Post Menopausal Women Phase 3
Not yet recruiting NCT05858931 - Hysteroscopic Evaluation and the Clinical Outcomes of Vaginal Repair of Cesarean Section Scar Defects
Completed NCT04232930 - The Use of Music in Reducing Pain During Outpatient Hysteroscopy N/A