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Clinical Trial Summary

Guidelines for noninvasive ventilation (NIV) recommend continuous positive airway pressure in patients with thoracic trauma who remain hypoxic . However, no any suggestion was applied for high flow nasal cannula (HFNC). Therefore, Our aim was to determine whether HFNC reduces intubation in severe trauma-related hypoxemia.


Clinical Trial Description

This would be a three-center randomized clinical trial of a level I trauma hospital. Inclusion criteria were patients with Arterial oxygen level (Pao2/)fraction of inspired oxygen inspired oxygen fraction(Fio2)<300 while receiving oxygen by high-flow mask within the first 72 h after thoracic trauma. Patients were randomized to remain on high-flow oxygen mask/ noninvasive ventilation or to receive HFNC. The interface was selected based on the associated injuries. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05828030
Study type Interventional
Source National Taiwan University Hospital
Contact Hsien-Chi Liao, MD
Phone +886-972651611
Email polarisliao@hotmail.com
Status Recruiting
Phase N/A
Start date April 25, 2023
Completion date December 31, 2024

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