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Hypoxia clinical trials

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NCT ID: NCT06060093 Completed - Sleep Clinical Trials

Effect of Ketone Ester Supplementation on Sleep and Recovery in Hypoxia

Start date: February 20, 2023
Phase: N/A
Study type: Interventional

This study specifically aims to elucidate the effects of IEK on sleep and recuperation in hypoxia, after training in normoxia. These conditions are in line with the widely applied live-high train-low strategy. Moreover, blood and tissue oxygenation status, as well as cerebral blood flow and cognitive function will be assessed.

NCT ID: NCT06054022 Completed - Atelectasis Clinical Trials

Usage of High Flow Nasal Cannula in Preventing Desaturations in Elderly Patients Going for Lower Limb Surgeries

Start date: July 7, 2020
Phase: N/A
Study type: Interventional

To study the effect of high flow nasal cannula in comparisons with nasoprong used intraoperatively in patients oxygenation status

NCT ID: NCT06016998 Completed - Clinical trials for Hypoxemia During Surgery

Prediction Model of Hypoxemia in Gastrointestinal Endoscopy Sedation

Start date: September 1, 2023
Phase:
Study type: Observational

The incidence of hypoxemia during gastrointestinal endoscopy sedation is high, but there is still a lack of perfect prediction model of hypoxemia, which often leads to unpredictable respiratory complications. In order to ensure the safety of gastrointestinal endoscopy sedation and make emergency plans in advance, a better diagnostic model is urgently needed to help assess the risk of hypoxemia in patients undergoing the process and make early intervention measures. Facial photography is a simple and feasible measure that can show the facial soft tissue and structure of bone. The purpose of this study is to explore whether facial photography combined with other clinical indicators can build a prediction model of hypoxemia during gastrointestinal endoscopy sedation.

NCT ID: NCT06000332 Completed - Nocturnal Hypoxemia Clinical Trials

Evaluation of POC Pulse-dose Demand Oxygen Delivery for Nocturnal Hypoxemia

Start date: October 17, 2023
Phase: N/A
Study type: Interventional

The aim of this study is to describe the effect of the Inogen Rove 6 Portable Oxygen Concentrator on peripheral oxygen saturation in adults receiving supplemental oxygen at night and examine whether the device can adequately maintain oxygen saturation during sleep.

NCT ID: NCT05991778 Completed - Septic Shock Clinical Trials

Bioelectrical Impedance in Monitoring Hyperhydration and Polyneuromyopathy in Critically Ill Patients

Start date: March 1, 2021
Phase:
Study type: Observational

This prospective, blinded observational clinical study was aimed to determine the effect of hyperhydration and muscle loss measured by Bioelectrical impedance vector analysis (BIVA) on mortality. The aim was to compare hydratation parameters measured by BIVA: OHY, Extracellular Water (ECW) / Total Body Wate (TBW) and quadrant, vector length, phase angle (PA) with cumulative fluid balance (CFB) recording (input-output) in their ability in predicting mortality as the abilities of the prognostic markers PA (BIVA), Acute Physiology and Chronic Health Evaluation II (APACHE II - score) and presepsin (serum Cluster of Differentiation (CD) 14-ST). The investigators also compared BIVA nutritional indicators (SMM, fat) with BMI and laboratory parameters (albumin, prealbumin and C-reactive protein (CRP) inflammation parameters) in the prediction of mortality. An important goal was to evaluate the usability of the BIVA method in critically ill patients on extracorporeal circulation, to compare the impedance data of the extracorporeal membrane oxygenation (ECMO) and non-ECMO groups.

NCT ID: NCT05972304 Completed - Hypoxia Clinical Trials

Efficiency and Safety of Nasal Positive Airway Pressure Systems During Endoscopy

Endo-Breath
Start date: April 1, 2022
Phase: N/A
Study type: Interventional

Goal of our study is to investigate whether the implication of nasal positive airway pressure (nPAP) system on patients with high periprocedural risk could significantly lower the incidence of severe hypoxia and hypercarbia. Furthermore, we have set up goals to assess key components and factors, which lead to development of hypercarbia during endoscopy.

NCT ID: NCT05967767 Completed - Hypoxia Clinical Trials

Repeated Sprint Training in Normobaric Hypoxia

Start date: November 1, 2022
Phase: N/A
Study type: Interventional

The aim of the current study was to examine the effects of 3-session repeated sprint training performed in a normobaric hypoxic condition with 48-hour rest intervals on sprint performance indices, arterial oxygen saturation (SpO2) and rating of perceived exertion (RPE) scores. Twenty-four moderately-trained males participated in this study voluntarily basis. This study was conducted on single-blind placebo-controlled design. Participants were divided into three groups as follows; normobaric hypoxia (3420 m; HYP), normobaric normoxia (162 m; PLA) and control group (CON). HYP and PLA groups subjected to 3 repeated sprint training session (4 set x 5 x 5 s sprints with 30 s recovery and 5 min rest between the sets) in normobaric hypoxia or normoxia condition. Pre- and pos-test were conducted 72 hours before and after the training intervention period. All the training and testing sessions performed in cycle ergometer. There were no detected significant time and condition interaction in the variables; relative peak power output (PPO), mean power output (MPO), percentage of sprint decrement score (Sdec%) and RPE observed in the scope of pre- and post-test.

NCT ID: NCT05920278 Completed - Hypoxia Clinical Trials

Accuracy of Pulse Oximeters in Profound Hypoxia

Start date: October 26, 2022
Phase:
Study type: Observational

The goal of this study was to evaluate the accuracy of pulse oximeters over the range of 70-100%. Two devices were placed on each subject with one on the finger and the other on the fingertip. SpO2 measurements from these devices were compared to sampling of arterial blood during brief stable oxygen desaturation in healthy volunteers to evaluate the claimed range.

NCT ID: NCT05898685 Completed - Clinical trials for Intermittent Hypoxia

Effect of a Single Session of Intermittent Hypoxia on Hematological Variables

Start date: April 16, 2019
Phase: N/A
Study type: Interventional

The purpose of the study is to determine the effect of a single exposure of intermittent hypoxia on erythropoietin levels and hemoglobin mass in young adults, older adults and patients with type 2 diabetes.

NCT ID: NCT05866289 Completed - Oxygen Deficiency Clinical Trials

Awake Prone Positioning for COVID-19 Acute Hypoxaemic Respiratory Failure

Start date: March 1, 2020
Phase:
Study type: Observational [Patient Registry]

The objective of our study is to evaluate the effectiveness of prone position in preventing intubation or death in spontaneously ventilated patients with COVID-19 with acute respiratory failure.