Single Lung Ventilation Versus Two Lung Ventilation

Hypoxemia Clinical Trial

Official title:

Single Lung Ventilation Versus Two Lung Ventilation in Video Assisted Lung Surgeries

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT04981990
• Other study ID #: Anesth
• Status: Recruiting
• Phase: N/A
• Start date: March 1, 2021
• Est. completion date: August 25, 2021

Study information

• Verified date: August 2021
• Source: Ain Shams University
• Contact: Esraa Abdellatif
• Phone: 01119895491
• Email: esraa301993[@]gmail.com
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Hypoxia in single lung ventilation versus two lung ventilation in video assisted lung surgeries

Description:

Incidence of hypoxia in single lung ventilation by double lumen endotracheal tube "of choice in lung surgeries" versus incidence of hypoxia in two lung ventilation by conventional single lumen endotracheal tube "intermittent two lung ventilation"

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 60
• Est. completion date: August 25, 2021
• Est. primary completion date: August 25, 2021
• Accepts healthy volunteers: No
• Gender: All
• Age group: 21 Years and older

Eligibility

Inclusion Criteria:

• Age group: Adult patients from age of 21 years to 60 years

• Sex: Both sexes

• ASA Classification: patients with ASA classification II, III.

• Elective lung surgeries using video assisted thoracoscopic surgeries.

Exclusion Criteria:

• Patients refuse to give informed consent.

• ASA Classification: ASA IV.

• Failure of thoracoscopic surgeries and continue as open thoracotomy

• Patients with ischemic heart diseases, where hypoxemia might be preexisting, or patient be more vulnerable to hypoxemia whatever the technique or time of hypoxia.

• Emergency lung surgeries.

• Patients underwent previous lung surgeries of any cause.

• Patients with pathology to the non-operated side.

Related Conditions & MeSH terms

• Hypoxemia
• Hypoxia
• Single Lung Ventilation

Intervention

Procedure:
• Single lung ventilation by double lumen endotracheal tube
Single lung ventilation using double lumen endotracheal tube and isolation of the operated lung during surgery to create ideal surgical field
• Two lung ventilation by conventional single lumen endotracheal tube
Intermittent two lung ventilation so that no significant hypoxia occurs with creating optimum surgical field

Locations

Country	Name	City	State
Egypt	Aun Shams University Hospitals	Cairo

Sponsors (1)

Lead Sponsor	Collaborator
Ain Shams University

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Incidence of hypoxemia	Hypoxemia in single and two lung ventilation by serial arterial blood gases	Intraoperative to first 24 hours post operative
Secondary	Incidence of failure to correct Hypoxemia in single lung ventilation	Stop lung isolation and procedure using two lung ventilation to correct hypoxia	Intraoperative
Secondary	Incidence of failure of two lung ventilation to create optimum surgical field	Frequent stopping of ventilation and the surgent can't access the surgical field easily	Intraoperative
Secondary	Incidence of post operative complications	Any associated complications	First 24 hours post operative