Hypotension Clinical Trial
Official title:
The Effects of Nicardipine and Esmolol Applied for Controlled Hypotension in Rhinoplasty Procedures on Hemodynamics and Regional Renal Oxygenation
Verified date | September 2022 |
Source | Yuzuncu Yil University |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
In this study, the effects of nicardipine and esmolol applied for controlled hypotension in rhinoplasty on hemodynamics and regional renal oxygenation will be investigated.
Status | Completed |
Enrollment | 80 |
Est. completion date | August 30, 2022 |
Est. primary completion date | August 1, 2022 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years to 60 Years |
Eligibility | Inclusion Criteria: - Between 18-60 years of age, - ASA I-II, - undergoing elective rhinoplasty surgery, - it was decided to apply controlled hypotension, - BMI (body mass index) between 18-25 kg/m2, - informed about the subject and - patients with written consent Exclusion Criteria: - ASA III-IV patients, - hypertension disease, - using anticoagulant medication, - pregnancy, - kidney failure, - bleeding diathesis, - active infection, - allergy to drugs to be used, - BMI=30, - refusing to participate in the study, - hypothermic, - patients taking antibiotics, anticonvulsants, antiarrhythmics, cholinesterase inhibitors |
Country | Name | City | State |
---|---|---|---|
Turkey | Van yuzuncu Yil University, Dursun Odabas Medical Center | Van |
Lead Sponsor | Collaborator |
---|---|
Yuzuncu Yil University |
Turkey,
Lin S, McKenna SJ, Yao CF, Chen YR, Chen C. Effects of Hypotensive Anesthesia on Reducing Intraoperative Blood Loss, Duration of Operation, and Quality of Surgical Field During Orthognathic Surgery: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. J Oral Maxillofac Surg. 2017 Jan;75(1):73-86. doi: 10.1016/j.joms.2016.07.012. Epub 2016 Jul 25. Review. — View Citation
Pilli G, Güzeldemir ME, Bayhan N. Esmolol for hypotensive anesthesia in middle ear surgery. Acta Anaesthesiol Belg. 1996;47(2):85-91. — View Citation
Steppan J, Hogue CW Jr. Cerebral and tissue oximetry. Best Pract Res Clin Anaesthesiol. 2014 Dec;28(4):429-39. doi: 10.1016/j.bpa.2014.09.002. Epub 2014 Sep 28. Review. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Level of hypotension | Measuring mean blood pressures | 1 year | |
Primary | Monitoring of renal oxygen saturation | Measurement of regional renal oxygenation | 1 year |
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