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Evaluating Fluid Strategies in Thoracic Surgery Patients Utilizing a Goal Directed Approach

Hypotension Clinical Trial

Official title:
Evaluating Fluid Strategies in Thoracic Surgery Patients Utilizing a Goal Directed Approach

Clinical Trial Summary

The purpose of this study is to conduct a prospective, randomized, controlled trial comparing a restrictive vs. conservative fluid strategy in thoracic surgery patients. Excessive perioperative fluid has been retrospectively implicated in the development postoperative acute lung injury (PALI) and pulmonary edema following lung resection. However, fluid restriction in these patients is not without risk and may compromise end organ perfusion (i.e. acute kidney injury). The hypothesis is that a conservative fluid approach in thoracic surgery patients will result in better end organ perfusion with fewer occasions of acute kidney injury (AKI) without causing an increase in postoperative acute lung injury or pulmonary edema.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02135146
Study type Interventional
Source University of Colorado, Denver
Contact
Status Completed
Phase Phase 4
Start date January 2014
Completion date September 2016
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