Hypotension Clinical Trial
Official title:
The Feasibility of PetCO2 Prediction Hypotension Under Spinal Anesthesia for Cesarean Section
Maternal hypotension is a common side effect after spinal anesthesia for cesarean
delivery.Decreased vascular resistance and cardiac output, due to sympathetic blockade1and
blood pooling in blocked areas of the body respectively, are main causes of spinal
anaesthesia-induced hypotension during Caesarean delivery.
Cardiac output, which has shown to be a better predictor of organ and placental perfusion
than arterial blood pressure.Few studies have measured CO after spinal anesthesia in the
maternal population.This is largely because of the lack of availability of accurate and
reproducible noninvasive measurement techniques. Up to now, preventing hypotension has
continued to focus on arterial blood pressure variables, fluid, and ephedrine requirements
as markers of cardiovascular status, because these are more easily measured.
Investgators hypothesized that CO and PetCO2, in parturients with the degree of hypotension
during spinal anaesthesia, would also have a positive and significant association.
Status | Recruiting |
Enrollment | 6 |
Est. completion date | February 2014 |
Est. primary completion date | February 2014 |
Accepts healthy volunteers | No |
Gender | Female |
Age group | 20 Years to 40 Years |
Eligibility |
Inclusion Criteria: - full-term gestation (>36 and <41 weeks of gestation) with a singleton pregnancy Exclusion Criteria: - emergency cases - placenta praevia - preeclampsia - cardiovascular or cerebrovascular disease - morbid obesity with a BMI=40 - contraindications to spinal anaesthesia |
Observational Model: Case-Only, Time Perspective: Prospective
Country | Name | City | State |
---|---|---|---|
China | Obstetrics & Gynecology Hospital, Fudan University | Shanghai | Shanghai |
Lead Sponsor | Collaborator |
---|---|
Geng guiqi |
China,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | value of PetCO2 and changes in artery pressure | up to 4 weeks | Yes |
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT04062994 -
A Clinical Decision Support Trial to Reduce Intraoperative Hypotension
|
||
Active, not recruiting |
NCT02016599 -
Effects of Transitional Circulation in ELBW Infants
|
||
Recruiting |
NCT05836610 -
Hydrocortisone Therapy Optimization During Hypothermia Treatment in Asphyxiated Neonates
|
Phase 4 | |
Suspended |
NCT02315937 -
Hemodynamic Assessment During Spinal Anesthesia Using Transthoracic Echocardiography'
|
N/A | |
Completed |
NCT03215797 -
Phenylephrine or Norepinephrine for a Better Hemodynamic Stability
|
Phase 3 | |
Completed |
NCT02907931 -
Carotid Doppler Ultrasound for the Measurement of Intravascular Volume Status
|
N/A | |
Recruiting |
NCT02532270 -
Detecting Hypotension By Continuous Non-invasive Arterial Pressure Monitoring
|
N/A | |
Completed |
NCT02437799 -
Dicrotic Notch and Hypotension at Caesarean Under Spinal Anaesthesia
|
N/A | |
Completed |
NCT02802683 -
Hemodynamic Impact of Hyperbaric Versus Isobaric for Spinal Anesthesia During Cesarean Delivery
|
Phase 4 | |
Completed |
NCT02146898 -
The Severity Of Hypotension Comparing Three Positions During Spinal Anesthesia For Cesarean Delivery
|
N/A | |
Completed |
NCT01930227 -
Transcutaneous Electrical Acupoint Stimulation(TEAS) for Hypotension After Spinal Anesthesia in Parturients
|
N/A | |
Not yet recruiting |
NCT01941472 -
Transcutaneous pO2, Transcutaneous pCO2 and Central Venous pO2 Variations to Predict Fluid Responsiveness
|
N/A | |
Recruiting |
NCT01434251 -
Treatment of Hypotension of Prematurity (TOHOP)
|
N/A | |
Withdrawn |
NCT01183741 -
Accuracy of Non-Invasive Blood Pressure Measurement in Adults
|
Phase 3 | |
Completed |
NCT01592669 -
Passive Leg Raising Attenuates and Delays Tourniquet Deflation-induced Hypotension and Tachycardia
|
N/A | |
Completed |
NCT00991627 -
Different Approaches to Maternal Hypotension During Cesarean Section
|
Phase 4 | |
Withdrawn |
NCT00750516 -
Lactic Acid Levels In Hypotensive Patients Without(Standard) and With Tourniquet
|
||
Completed |
NCT00115726 -
Trial Assessing the Effect of Preoperative Furosemide on Intraoperative Blood Pressure
|
Phase 4 | |
Recruiting |
NCT05513066 -
Management Arterial Hypotension During Planned Caesarean Section, Intravenous Ephedrine/Phenylephrine Mixture Versus Intravenous Baby Noradrenaline
|
||
Completed |
NCT04089644 -
Manual vs Closed-loop Control of Mean Arterial Pressure
|
N/A |