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Hypotension clinical trials

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NCT ID: NCT03842046 Completed - Clinical trials for Cesarean Section Complications

Prevention of Hypotension During Cesarean Section

NOR-PHEN
Start date: February 16, 2019
Phase: N/A
Study type: Interventional

The aim of this double-blind randomized study will be to compare a fixed-rate prophylactic noradrenaline infusion to a fixed-rate prophylactic phenylephrine infusion during elective cesarean section under combined spinal-epidural anesthesia

NCT ID: NCT03837535 Completed - Myocardial Injury Clinical Trials

Myocardial Infarction in the Perioperative Setting

MIPS
Start date: January 1, 2019
Phase:
Study type: Observational [Patient Registry]

Acute myocardial infarction (AMI) is a significant complication following non-cardiac surgery. The investigators sought to evaluate incidence of perioperative AMI, its preoperative and intraoperative risk factors and the outcomes after this complication.

NCT ID: NCT03834454 Completed - Clinical trials for Postoperative Complications

Bupivacaine 5 mg vs 7.5 mg for Spinal Anesthesia in Cesarean Delivery in Indonesian Population

Start date: October 1, 2013
Phase: N/A
Study type: Interventional

This study aims to evaluate the efficacy of hyperbaric 5 mg bupivacaine + fentanyl 25 mcg versus hyperbaric 7.5 mg bupivacaine + fentanyl 25 mcg to lower incidence of hypotension

NCT ID: NCT03834259 Completed - Hypotension Clinical Trials

The Effects of Keeping the Patient in a Sitting Position for One Minute After Spinal Anesthesia

Start date: January 1, 2017
Phase: N/A
Study type: Interventional

The aim of this study was to examine the effect of keeping the patient in a sitting position for 1 minute after spinal anaesthesia in elective caesarean operations, primarily on the formation of hypotension and secondarily on nausea-vomiting, the need for ephedrine and the block characteristics.

NCT ID: NCT03829657 Terminated - Clinical trials for Parkinson's Disease (PD)

Phase 3 Clinical Effect Durability of TD-9855 for Treating Symptomatic nOH in Subjects With Primary Autonomic Failure

REDWOOD
Start date: February 22, 2019
Phase: Phase 3
Study type: Interventional

A Phase 3, 22-week, Multi-center, Randomized Withdrawal Study of ampreloxetine in Treating Symptomatic Neurogenic Orthostatic Hypotension in Subjects with Primary Autonomic Failure

NCT ID: NCT03809065 Completed - Tissue Perfusion Clinical Trials

Effects of Nitroglycerin Versus Labetalol on Tissue Perfusion During Deliberate Hypotension

Start date: January 19, 2019
Phase: Phase 4
Study type: Interventional

Deliberate hypotension is used to provide bloodless field during endoscopic sinus surgery; however, hypotension might impair perfusion of vital organs. The aim of this work is to compare the impact of nitroglycerin and labetalol on peripheral perfusion when used for induction of deliberate hypotension

NCT ID: NCT03805217 Active, not recruiting - Hypotension Clinical Trials

Hypotension Prediction Index Study (HPI Study)

Start date: May 16, 2019
Phase:
Study type: Observational

A prospective, single-arm, open-label, multicenter post-approval study to determine whether the use of the Acumen HPI Software to guide intraoperative hemodynamic management in non-cardiac surgery reduces the duration of intraoperative hypotension below a threshold of Mean Arterial Pressure (MAP)

NCT ID: NCT03795831 Recruiting - Clinical trials for Intraoperative Hypotension

Validation Study in Patients of a Non-invasive Blood Pressure Monitor for Perioperative Use

Start date: March 1, 2017
Phase:
Study type: Observational [Patient Registry]

Collecting all available data (waveforms, beat to beat data, status data) generated by a non invasive blood pressure monitor on each hand and compare this to the actual data obtained by intra arterial (radial) monitoring. This to see if the non invasive bloodpressure monitor can be validated for intraoperative use.

NCT ID: NCT03792906 Completed - Clinical trials for Cesarean Section Complications

Comparison of Two Norepinephrine Bolus Doses for Management of Post-spinal Hypotension During Cesarean Delivery

Start date: January 18, 2019
Phase: Phase 4
Study type: Interventional

In this study the investigators will compare two doses of norepinephrine bolus (6 mcg and 10 mcg) in management of maternal hypotensive episode after subarachnoid block during Cesarean delivery.

NCT ID: NCT03787732 Completed - Clinical trials for Acute Respiratory Failure

Preventing Cardiovascular Collapse With Administration of Fluid Resuscitation During Induction and Intubation

PREPARE II
Start date: February 1, 2019
Phase: Phase 4
Study type: Interventional

Complications are common during tracheal intubation of critically ill patients. Nearly one in five patients undergoing intubation in the intensive care unit experiences cardiovascular collapse, defined as severe hypotension, vasopressor administration, cardiac arrest or death. Cardiovascular collapse during intubation is associated with increased resource utilization and decreased survival. Administration of 500 mL of intravenous crystalloid solution beginning prior to induction may prevent cardiovascular collapse. The only prior trial examining fluid bolus administration during intubation found no effect on cardiovascular collapse or clinical outcomes overall, but a hypothesis-generating subgroup analysis suggested potential benefit to fluid bolus administration among patients receiving positive pressure ventilation between induction and laryngoscopy. Therefore, we propose a randomized trial comparing fluid bolus administration versus none with regard to cardiovascular collapse among critically adults undergoing intubation with positive pressure ventilation between induction and laryngoscopy.