Long Term Outcome of Hypospadias Repair

Status Completed

Clinical Trial Summary

Hypospadias is a common congenital abnormality of the penis which affects approximately 1 boy in 250. The opening of the urethra is located on the undersurface of the penis rather than the tip,the foreskin is deficient and there is curvature of the penile shaft in more severe cases. Although the most commonly practised corrective operation ( TIP procedure) gives generally good results, recently published evidence points to a possible long term risk of stenosis ( narrowing of the reconstructed urethra). This comparative study will combine clinical assessment with non invasive measurements of urinary flow to assess the functional outcome of a large series of patients who have undergone hypospadias surgery . The study is primarily designed to answer this question : does a modification of the standard operation which incorporates a skin graft into the reconstructed urethra lead to improved urinary flow and a decreased risk of stenosis? This has not been previously studied . The findings of our study could make an important contribution to improvements in the surgical treatment of boys born with hypospadias.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Hypospadias

Clinical Trial Details

NCT number	NCT02103712
Study type	Observational
Source	The Leeds Teaching Hospitals NHS Trust
Contact
Status	Completed
Phase
Start date	October 1, 2012
Completion date	September 30, 2013

View Details

See also
Status	Clinical Trial	Phase
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Not yet recruiting	`NCT03698721` - Urothelium Tissue Engineering Using Biopsies From Transurethral Resection of Prostate
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Recruiting	`NCT05319782` - Long-term Assesment of Patients Operated for Hypospadias in Their Childhood : Urinary, Aesthetical, Sexual and Psycho-social Consequences	N/A
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Completed	`NCT05144659` - Evaluation of Double Faced Transverse Preputial Onlay Island Flap for Hypospadias Repair in Pediatrics	N/A
Suspended	`NCT05708989` - Caudal vs. Pudendal Block in Peds GU	Phase 4