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Hypophosphatasia (HPP) clinical trials

View clinical trials related to Hypophosphatasia (HPP).

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NCT ID: NCT02104219 Completed - Clinical trials for Hypophosphatasia (HPP)

Retrospective, Non-interventional Natural History of Patients With Juvenile-onset Hypophosphatasia (HPP)

Start date: March 2014
Phase:
Study type: Observational

The purpose of this study is to characterize the natural history of HPP in patients with Juvenile-onset HPP.

NCT ID: NCT01419028 Completed - Clinical trials for Hypophosphatasia (HPP)

A Retrospective Study of the Natural History of Patients With Severe Perinatal and Infantile Hypophosphatasia (HPP)

Start date: August 2012
Phase:
Study type: Observational

This study aims to characterize the natural history of patients with severe perinatal or infantile onset HPP.

NCT ID: NCT01203826 Completed - Clinical trials for Hypophosphatasia (HPP)

Extension Study of Protocol ENB-006-09 - Study of Asfotase Alfa in Children With Hypophosphatasia (HPP)

Start date: April 2010
Phase: Phase 2
Study type: Interventional

This clinical trial studies the long term safety and efficacy of asfotase alfa in children with HPP who completed Study ENB-006-09 (NCT00952484).

NCT ID: NCT00952484 Completed - Clinical trials for Hypophosphatasia (HPP)

Safety and Efficacy of Asfotase Alfa in Juvenile Patients With Hypophosphatasia (HPP)

Start date: September 2009
Phase: Phase 2
Study type: Interventional

This clinical trial studied the safety and efficacy of asfotase alfa in children with HPP compared to a historical control group.

NCT ID: NCT00744042 Completed - Clinical trials for Hypophosphatasia (HPP)

Safety and Efficacy Study of Asfotase Alfa in Severely Affected Infants With Hypophosphatasia (HPP)

Start date: September 2008
Phase: Phase 1/Phase 2
Study type: Interventional

This clinical trial studies the safety and efficacy of asfotase alfa in infants and young children with infantile onset HPP.

NCT ID: NCT00739505 Completed - Clinical trials for Hypophosphatasia (HPP)

Safety Study of Human Recombinant Tissue Non-Specific Alkaline Phosphatase Fusion Protein Asfotase Alfa in Adults With Hypophosphatasia (HPP)

Start date: August 2008
Phase: Phase 1
Study type: Interventional

This clinical trial studies the safety, tolerability, and pharmacology of asfotase alfa when given to adults with HPP.