Hypoperfusion Clinical Trial
Official title:
Effects of Citrulline on Gut Functioning During Excercise
During exercise, splanchnic perfusion is compromised, resulting in organ damage in healthy individuals. Improving the availability of NO might result increase splanchnic perfusion and prevent organ damage during exercise.
Status | Enrolling by invitation |
Enrollment | 30 |
Est. completion date | February 2012 |
Est. primary completion date | January 2012 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | Male |
Age group | 18 Years to 35 Years |
Eligibility |
Inclusion Criteria: - male - age 18-35 years Exclusion Criteria: - not healthy - use of medication or related products - alcohol misuse - smoking |
Allocation: Randomized, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Investigator, Outcomes Assessor), Primary Purpose: Prevention
Country | Name | City | State |
---|---|---|---|
Netherlands | Maastricht University Medical Center | Maastricht | Limburg |
Lead Sponsor | Collaborator |
---|---|
Maastricht University Medical Center | Top Institute Food and Nutrition |
Netherlands,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | GI perfusion | 2 hours | No | |
Primary | gut damage | 5 hours | No | |
Primary | microcirculation | 5 hours | No | |
Secondary | liver damage | 5 hours | No | |
Secondary | kidney damage | 5 hours | No | |
Secondary | amino acid analysis | 5 hours | No |
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