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NCT01341665 Clinical Trial

Subclassification of the Syndrome of Inappropriate ADH Secretion

Hyponatremia Clinical Trial

Official title:
Subclassification of the Syndrome of Inappropriate Antidiuresis Via Copeptin - What is the Genesis of ADH-independent SIADH?

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT01341665
Other study ID # 5/08
Secondary ID
Status Completed
Phase N/A
First received April 21, 2011
Last updated April 25, 2011
Start date March 2008
Est. completion date April 2011

Study information
Verified date April 2011
Source University of Wuerzburg
Contact n/a
Is FDA regulated No
Health authority Germany: Ethics Commission
Study type Observational

Clinical Trial Summary

The aim of this study is to evaluate the different types of osmotic dysregulation in patients with Syndrome of Inappropriate ADH (SIADH) and, hence, to analyze the pathophysiology of SIADH.

These types will be characterized by measurement of AVP and copeptin while performing an osmotic stimulation with infusion of hypertonic saline.

Recruitment information / eligibility
Status Completed
Enrollment 50
Est. completion date April 2011
Est. primary completion date April 2011
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Both
Age group 18 Years to 90 Years
Eligibility Inclusion Criteria:

- age > 18 years,

- hyponatremia < 132 mmol/L

- SIADH

Exclusion Criteria:

- age < 18 years

- cerebral metastases

- serum sodium > 132mmol/L

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Related Conditions & MeSH terms

Locations
Country Name City State
Germany University of Wuerzburg Wuerzburg Bavaria

Sponsors (1)
Lead Sponsor Collaborator
University of Wuerzburg

Country where clinical trial is conducted

Germany, 

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