Clinical Trials Logo
  1. Home
  2. Hypertriglyceridemia
  3. NCT05487833
  4. Details
NCT05487833 Clinical Trial

Insulin and Standard Management in Hypertriglyceridemic Acute Pancreatitis

Hypertriglyceridemia Clinical Trial

Official title:
Comparison of Insulin and Standard Management in Hypertriglyceridemic Acute Pancreatitis in Patients Without Diabetes

Clinical Trial Details — Status: Not yet recruiting

Administrative data
NCT number NCT05487833
Other study ID # InzulinHTGAP
Secondary ID
Status Not yet recruiting
Phase Phase 4
First received
Last updated
Start date November 2022
Est. completion date September 2024

Study information
Verified date October 2022
Source University Medical Centre Ljubljana
Contact Samo Plut, MD
Phone 00386 1 522 4165
Email samo.plut@kclj.si
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

To compare the efficacy of infusion containing insulin and infusion without insulin on reduction of triglycerides in acute hypertriglyceridemic pancreatitis

Recruitment information / eligibility
Status Not yet recruiting
Enrollment 30
Est. completion date September 2024
Est. primary completion date September 2024
Accepts healthy volunteers No
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: - acute pancreatitis - triglycerides > 15 mmol/l Exclusion Criteria: - diabetes on peroral therapy or insulin - blood glucose > 11 mmol/l - pregnancy

Study Design

Related Conditions & MeSH terms

Intervention

Biological:
• insulin
5% glucose in 0.9% NaCl with 4 IU of short acting insulin per 500 ml added, infused at a rate determined by the treating physician, treatment duration: 18 hours
Other:
• standard treatment
infusion of a balanced solution, infused at a rate determined by the treating physician, treatment duration: 18 hours

Locations
Country Name City State
n/a

Sponsors (1)
Lead Sponsor Collaborator
University Medical Centre Ljubljana

Outcome
Type Measure Description Time frame Safety issue
Primary %triglyceride reduction change in triglycerides, expressed as % of initial value after 18 hours of treatment
Secondary incidence of hypoglycemia during treatment with insulin, up to day 5
See also
  Status Clinical Trial Phase
Completed NCT03929198 - Translation of Pritikin Program to the Community N/A
Completed NCT02250105 - Trial of ARI-3037MO to Reduce Triglyceride Levels in Adults With Severe (≥500 mg/dl) Hypertriglyceridemia Phase 2
Completed NCT02859129 - Study to Evaluate the 2-Way Interaction Between Multiple Doses of Epanova™ and a Single Dose of Rosuvastatin (Crestor®) Phase 1
Completed NCT01455844 - TRIal For Efficacy of Capre on hyperTriglyceridemiA Phase 2
Completed NCT01437930 - Intervention With n-3 Polyunsaturated Fatty Acids (PUFA)-Supplemented Products in Moderate Hypertriglyceridemic Patients N/A
Completed NCT01010399 - Boosted Lexiva With Lovaza Adjunctive Therapy in Hypertriglyceridemic, HIV-Infected Subjects Phase 4
Completed NCT00959842 - Effects of Lovaza on Lipoprotein Composition and Function in Mild Hypertriglyceridemia Phase 1/Phase 2
Completed NCT00519714 - A Study to Evaluate the Lipid Regulating Effects of 1-Methylnicotinamide (1-MNA) Phase 2/Phase 3
Recruiting NCT00186537 - Comparing Tricor, Avandia, or Weight Loss to Lower Cardiovascular Risk Factors in People With High Triglycerides. N/A
Completed NCT00246402 - Acipimox to Improve Hyperlipidemia and Insulin Sensitivity Associated With HIV N/A
Completed NCT06020950 - Chia Seeds Consumption in Hypertriglyceridemia N/A
Completed NCT02354976 - A Double-blind Randomized Placebo-controlled Study Comparing Epanova and Fenofibrate on Liver Fat in Overweight Subjects. Phase 2
Completed NCT04966494 - Impact of Beans and Oats Snack Bar on Hypertriglyceridemic Women N/A
Completed NCT04650152 - Study to Assess Tricor Therapy Effectiveness in Patients With Metabolic Syndrome (TRISTAN)
Completed NCT04630366 - A Phase 1, First Time in Humans Study of NST-1024 Phase 1
Completed NCT03693131 - Efficacy of MND-2119 in Participants With Hypertriglyceridemia Phase 3
Completed NCT04756180 - An Efficacy and Safety Study of Omega-3-acid Ethyl Ester in Chinese Subjects With Hypertriglyceridemia. Phase 3
Completed NCT02868177 - Effect of Totum-63, Active Ingredient of Valedia, on Glucose and Lipid Homeostasis on Subjects With Prediabetes Phase 2/Phase 3
Completed NCT01968720 - Pilot Study To Assess CAT-2003 in Patients With Severe Hypertriglyceridemia Phase 2
Completed NCT01462877 - A Study to Evaluate Fenofibrate Combination With Statin in Chinese Patients With Dyslipidemic Phase 4