Activation of miRNA & Proteins After Acute Experimental Pain. (miRNA:

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Clinical Trial Summary

In this experiment, the investigators would like to test the following: 1. Does acute pain induced by hypertonic injection cause changes in plasma miRNA and protein expression ? 2. Can these canges correlate with the development of local hyperalgesia? 3. How does the plasma miRNA expression change over a duration of 24 hours post pain induction ? 4. Which mRNA targets are potentially affected by acute pain?

See also
Status	Clinical Trial	Phase
Recruiting	`NCT06226402` - Effect of Nebulized and Intravenous Hypertonic Saline 3% on the Management of Patients With Acute Respiratory Distress Syndrome	N/A
Completed	`NCT04146311` - Effect of Short-term Motor Training on Accuracy and Precision of Knee Movement in Human With and Without Knee Pain	N/A
Completed	`NCT04686344` - Point of Care Optic Nerve Sheath Ultrasound to Assess Intracranial Pressure	Early Phase 1

NCT number	NCT04439994
Study type	Interventional
Source	Aalborg University
Contact
Status	Completed
Phase	N/A
Start date	November 1, 2020
Completion date	July 1, 2022

Activation of miRNA and Proteins After Acute Experimental Pain. (miRNA: Micro RNA) — miRNA

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms