Serum Tryptase Concentration During General Anaesthesia With Rocuronium

Status Completed

Clinical Trial Summary

Rocuronium is a aminosteroid structured, non-depolarizing neuromuscular blocking agents (NMB). Epidemiological data presents that the frequency of hypersensitivity reactions caused by rocuronium have been increased. Determinations of serum tryptase concentrations are interdisciplinary recommended in diagnosis of its adverse reactions. No studies have been performed to explain specific role of rocuronium doses on serum tryptase values. The aim of this study was to investigate the potential effect of rocuronium on serum tryptase concentrations.

Clinical Trial Description

The greatest risk of hypersensitivity occurs during anesthesia for female patients and it is connected with the induction phase using skeletal muscle relaxants . Epidemiological data presents that the frequency of hypersensitivity reactions caused by rocuronium have been increased. Due to the multiple advantages reports of triggering allergic or hypersensitivity reactions caused by rocuronium create doubts about the safety of application . ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04035707
Study type	Interventional
Source	Medical University of Bialystok
Contact
Status	Completed
Phase	N/A
Start date	June 25, 2009
Completion date	May 15, 2014

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