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Hypersensitivity, Food clinical trials

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NCT ID: NCT04239131 Recruiting - Clinical trials for Hypersensitivity, Food

Prospective Study About Sensitization Pattern to Insects as Food Source in Patients With House Dust Mite Allergy

InFood
Start date: March 15, 2021
Phase: N/A
Study type: Interventional

Patients allergic to seafood and/or sensitized to Tropomyosin of Skin Prick tests SPT or crustacean origin will may be also be sensitized to edible insects. Aim of the study is to evaluate whether patients allergic to seafood and/or sensitized to Tropomyosin of SPT or crustacean origin may be more often be sensitized to edible insects used as food source.

NCT ID: NCT03679676 Recruiting - Food Allergy Clinical Trials

Clinical Study Using Biologics to Improve Multi OIT Outcomes (COMBINE)

Start date: February 5, 2020
Phase: Phase 2
Study type: Interventional

Food allergy (FA) is a serious public health concern that causes potentially-life threatening reactions in affected patients. The prevalence of food allergy in the United States (U.S.) has increased substantially and now affects 15 million patients:4-8% of children (6 million children, 30% with multiple food allergies) and about 9% of adults. This is a prospective Phase 2, single-center, multi-allergen OIT study in participants with proven allergies to 2 or 3 different foods in which one must be a peanut. The total of participants in the clinical study will be 110, ages 4 to 55 years with a history of multiple food allergies of 2 to 3 different foods including peanut. Allergy will be confirmed by FA-specific IgE levels and positive skin prick test (SPT). Enrolled participants must be positive during the Double-blind Placebo-controlled Food challenge (DBPCFC) at or before the 300 mg (444 mg cumulative) dosing level of FA proteins.