Hyperplasia Clinical Trial
Official title:
The Castleman Disease Collaborative Network Biobank: A Collection of Biospecimens and Clinical Data to Facilitate Research
The purpose of this study is to create a biobank, which collects, stores, and distributes samples of human tissues, blood, and related health information to qualified scientists, in order to help doctors and researchers better understand why Castleman Disease occurs and develop ways to better treat and prevent it.
The CDCN proposes to establish a biobank and associated clinical data for Castleman disease.
Tissue and fluid (blood and saliva) samples will be collected both prospectively and
retrospectively. Blood or saliva samples may also be collected from relatives of Castleman
patients. Because of the scarcity of these samples, it will be necessary to make efforts to
access all available cases. Many cases will occur at hospitals that do not have an existing
relationship with the CDCN and may not have experience with tissue procurement; however, this
is the only way to obtain the vast majority of samples. Samples may be used immediately,
banked for future use, or further processed into DNA, cell lines, tissue microarrays, etc.
The samples will be stored at Precision for Medicine, a biorepository company that
specializes in collection, processing, storage and distribution of biospecimens. Only
researchers (US or international) who have applied to the CDCN and have been approved by the
Biobank Advisory Board will be eligible to access biospecimens and/or data. The Biobank
Advisory Board will be comprised of clinicians and scientists with experience in clinical and
investigational practices in Castleman Disease.
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