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Hyperplasia clinical trials

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NCT ID: NCT02940392 Completed - Clinical trials for Benign Prostatic Hyperplasia

Rezum FIM Optimization Study

Rezum FIM
Start date: March 19, 2012
Phase: N/A
Study type: Interventional

Evaluate the effect of the NxThera BPH Rezum System on prostate tissue in subjects suffering from LUTS symptoms secondary to benign prostatic hyperplasia (BPH).

NCT ID: NCT02934399 Completed - Acromegaly Clinical Trials

Dynamic Hormone Diagnostics in Endocrine Disease

ultradian
Start date: October 2016
Phase:
Study type: Observational

The study will investigate 27 hour profiles of hormones in the subcutaneous tissue of healthy subjects and patients with Addison's, Congenital Adrenal Hyperplasia, Growth Hormone Deficiency, acromegaly, Cushings and Primary Hyperaldosteronism during conventional diagnostic and therapeutic follow-up. The 27 hour monitoring by ULTRADIAN takes into account the rhythm of hormones throughout the day. It is hoped that this information may in the future improve and simplify diagnostic procedures. Follow-up of patients in endocrinology still remains difficult including clinical signs of over and under-treatment, questionnaires of quality of life and blood testing necessitating often retesting. Simplification of the diagnostic procedure by obtaining detailed knowledge about the rhythm of hormones may contribute to the improvement and individualization of treatment and may decrease morbidity and mortality of endocrine patients.

NCT ID: NCT02930889 Completed - Clinical trials for Benign Prostatic Hyperplasia

Prostate Artery Embolization (PAE) for Lower Urinary Tract Symptoms (LUTS) Due to Benign Prostatic Hyperplasia (BPH)

Start date: October 1, 2016
Phase: N/A
Study type: Interventional

This is a investigator-initiated evaluation of the safety and efficacy of treating benign prostatic hyperplasia (BPH) by prostatic artery embolization.

NCT ID: NCT02928978 Recruiting - Clinical trials for Ductal Carcinoma In Situ

Ruxolitinib for Premalignant Breast Disease

TBCRC042
Start date: May 13, 2018
Phase: Phase 2
Study type: Interventional

This study is evaluating how ruxolitinib affects premalignant breast cells. One half of the study participants will receive ruxolitinib for approximately 15 days, and the other half will receive a placebo (sugar pill) for approximately 15 days. Once study participants have completed their ruxolitinib or placebo, participants will undergo surgery to remove the premalignant breast tissue.

NCT ID: NCT02918227 Terminated - Clinical trials for Benign Prostatic Hyperplasia

Exploration of Ejaculation Changing Mechanism After Surgery for Benign Prostatic Hyperplasia

EMMECH
Start date: December 8, 2016
Phase: N/A
Study type: Interventional

Every year in France, more than 60 000 people are operated for benign prostatic hyperplasia (BPH). This surgery is accompanied by a change or even a loss of ejaculations externalized what constitutes the main constraint for patients. Empirically, the investigators talk to the patient "retrograde ejaculation" to explain a possible loss of ejaculation. Yet the underlying mechanism of this modification or loss of ejaculation remains completely unknown. Yet the underlying mechanism of this modification or loss of ejaculation remains completely unknown. No study could not determine whether the predominant mechanism was a real retrograde ejaculation or aspermia. Moreover, technical changes are sometimes tempted to preserve antegrade ejaculation but no scientific rationale can not validate.

NCT ID: NCT02903797 Recruiting - Clinical trials for Endometrial Hyperplasia

Irisin Hormone Levels in Endometrial Hyperplasia

Start date: August 2016
Phase: N/A
Study type: Observational

The purpose of the study is to determine serum irisin hormone levels an its relation between endometrial hyperplasia

NCT ID: NCT02890641 Recruiting - Tuberous Sclerosis Clinical Trials

Genetic and Electrophysiologic Study in Focal Drug-resistant Epilepsies

GENEPHY
Start date: December 12, 2015
Phase:
Study type: Observational

Brain somatic mutations in genes belonging to the mTOR signaling pathway are a frequent cause of cortical malformations, including focal cortical dysplasia or hemimegalencephaly. The present study aims to search for brain somatic mutations in paired blood-brain samples and perform functional validation in children with drug-resistant focal epilepsy

NCT ID: NCT02873117 Completed - Clinical trials for Benign Prostate Hyperplasia

Evaluation of the Potential Association Between 5α-reductase Inhibitors Prescription and Occurrence of High Grade Prostate Cancers

CANARI
Start date: December 2014
Phase: N/A
Study type: Observational

This is a multicenter, cohort study based on medico-administrative data from pathology laboratory registries and drug reimbursement files (CNAM-TS).

NCT ID: NCT02872818 Completed - Clinical trials for Apoptotic Signal Pathways in Endometrial Hyperplasia

Apoptotic Signaling Pathways in Rats With Endometrial Hyperplasia

Start date: October 2014
Phase: Phase 4
Study type: Interventional

The purpose of the study is to determine apoptotic signaling pathways such as Survivin, Bcl-2, Bax, c-Myc and caspase-9 expression levels in rats model with iatrogenic endometrial hyperplasia after metformin and medroxyprogesterone acetate administration.

NCT ID: NCT02871050 Withdrawn - Hyperplasia Clinical Trials

Castleman Disease Collaborative Network Biobank

"Castlebank"
Start date: June 2016
Phase:
Study type: Observational

The purpose of this study is to create a biobank, which collects, stores, and distributes samples of human tissues, blood, and related health information to qualified scientists, in order to help doctors and researchers better understand why Castleman Disease occurs and develop ways to better treat and prevent it.