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Hyperpigmentation clinical trials

View clinical trials related to Hyperpigmentation.

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NCT ID: NCT03933774 Completed - Vitiligo Clinical Trials

PHNA, Efficacy of Tretinoin Cream on Post-phototherapy Hyperpigmentation

Start date: April 29, 2019
Phase: N/A
Study type: Interventional

A randomized controlled split-face pilot study was planned to investigate the preventive effect of tretinoin 0.05% cream on hyperpigmentation during phototherapy in patients with vitiligo.

NCT ID: NCT03926845 Completed - Clinical trials for Facial Hyperpigmentation

Efficacy and Tolerability of an Isobutylamido-thiazolyl-resorcinol Cream 0.2% for Facial Hyperpigmentation

Start date: April 29, 2019
Phase: N/A
Study type: Interventional

Facial hyperpigmentation is a common skin issue that can cause embarrassment and affect the quality of life in majority of people. The investigators are conducting a research to study an efficacy and tolerability of Isobutylamido-thiazolyl-resorcinol 0.2% in lightening of the facial hyperpigmentation in comparison to vehicle intervention in 4, 8 and 12-week period. The ultimate goal is to provide the best cosmetic cream to improve the quality of life of people who suffer from facial hyperpigmentation.

NCT ID: NCT03719274 Completed - Clinical trials for Melanin Hyperpigmentation

Vitamin C Depigmenattion Versus Conventional Technique

Start date: April 2016
Phase: N/A
Study type: Interventional

Although physiologic gingival hyperpigmentation is not a pathologic condition, it is considered one of the main esthetic problems in dentistry. It was found that the attached gingiva is the most frequently pigmented intraoral tissues followed by the papillary gingiva and the alveolar mucosa

NCT ID: NCT03457246 Completed - Hyperpigmentation Clinical Trials

Efficacy and Tolerance of D-pigment Versus Moisturizer in Hands' Lentigo Lesions With or Without Laser Therapy

Start date: May 6, 2013
Phase: N/A
Study type: Interventional

Pierre Fabre Dermo-Cosmétique has commercialized a cosmetic product (D-pigment rich texture) for treatment of hyperpigmentation. The aim of this study is to evaluate the efficacy of D-pigment after laser therapy, through its action on peri-lesional areas, in obtaining better cosmetic effect.

NCT ID: NCT03402893 Completed - Acne Vulgaris Clinical Trials

The Use of Onexton in Moderate Acne Vulgaris for Patients With Skin of Color

Start date: July 28, 2017
Phase: Phase 4
Study type: Interventional

This is a single-center, open label pilot study. The study is comprised of 5 study visits; Screening, Baseline, and Weeks 4, 8, and 16. All subjects will receive Onexton at Baseline and be instructed to apply the gel once daily to the face. The investigators will evaluate Investigator Global Assessment of acne (IGA), total lesion count, inflammatory lesion count, non-inflammatory lesion count, Investigator Global Assessment of Post-Inflammatory Hyperpigmentation and distribution of Post-Inflammatory Hyperpigmentation, adverse events and concomitant medications.

NCT ID: NCT03400202 Completed - Clinical trials for Periorbital Hyperpigmentation

Physiopathologic Aspects and Quality of Life in Participants With Eye Dark Circles

Start date: February 2, 2018
Phase:
Study type: Observational

This study will evaluate the physiopathologic characteristics of dark circles in participants with various ethnicities and Fitzpatrick Skin Types and the impact of the dark circles on the quality of life.

NCT ID: NCT03252418 Completed - Clinical trials for Gingival Hyperpigmentaion

Ascorbic Acid Versus Diode Laser in the Treatment of Gingival Hyperpigmentation

Start date: October 7, 2015
Phase: Phase 4
Study type: Interventional

Vitamin C affect the melanocytes function not the number while diode laser cause melanocytes destruction. Although diode laser and vitamin C have proved their effectiveness in depigmentation in previous studies, there are no published studies compared the effect of diode laser and vitamin C on melanocytes and melanosomes clinically and histologically.

NCT ID: NCT03114514 Completed - Clinical trials for Periorbital Hyperpigmentation

Efficacy of Platelet-rich Plasma (PRP) in the Treatment of Dark Circles Under the Eyes

Start date: June 17, 2016
Phase: N/A
Study type: Interventional

10 ml of blood from each patient will be drawn. This blood specimen will be centrifuged in a specific way to get 1 ml of platelet rich plasma (PRP). PRP will be injected into the the skin under the eyes. The treatment course consists of three sessions of PRP injections with one-month intervals between the sessions.

NCT ID: NCT02905903 Completed - Clinical trials for Post-inflammatory Hyperpigmentation

An In Vivo Model for Postinflammatory Hyperpigmentation

Start date: February 14, 2016
Phase: N/A
Study type: Interventional

Post-inflammatory hyperpigmentation (PIH) is an acquired hypermelanosis that occurs after cutaneous inflammation or injury that frequently affects darker skinned populations. Previously, a model of 35% TCA-induced PIH was validated against acne induced PIH, which has value in product testing for the treatment of PIH. In this second phase of the study, the investigators would like to determine if a lower concentration of TCA-induced PIH is comparable to acne-induced PIH.

NCT ID: NCT02492373 Completed - Clinical trials for Post Inflammatory Hyperpigmentation

Topical Corticosteroids on the Incidence of Postinflammatory Hyperpigmentation After QsNdYAG Laser

Start date: February 2015
Phase: N/A
Study type: Interventional

To investigate the benefit of the application of topical high potency steroid on the incidence of post inflammatory hyperpigmentation after laser treatment.