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Investigation on Differences in Skin Sodium Content Between Normal Subjects and ICU-patients — InCa  

Hypernatremia Clinical Trial

Official title:
Onderzoek Naar Intracutane Natriumopslag Bij Intensive Care patiënten (InCa-studie)

Clinical Trial Summary

This study investigates the differens in sodium storage in skin between normal subjects, patients after cardiac surgery and septic patients.

Clinical Trial Description

According to the current paradigm ICU-acquired hypernatremia is mainly an iatrogenic problem, caused by sodium overload or water deficit. In spite of several interventions to reduce sodium intake and optimize fluid balance, critically ill patients still develop hypernatremia. These patients also seem to have an inability to excrete sodium, hence develop a positive sodium balance. In animals sodium storage in the third compartment was found. Our hypothesis is that sodium storage in the third compartment is different in critically ill patients and this difference could play a role in the development of ICU-acquired hypernatremia. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02912299
Study type Observational
Source Medical Centre Leeuwarden
Contact
Status Completed
Phase N/A
Start date November 3, 2016
Completion date September 5, 2017
View Details
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