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Hyperkinesis clinical trials

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NCT ID: NCT04832737 Completed - Clinical trials for Attention Deficit Hyperactivity Disorder

Strength-based Treatment Approach for Adults With ADHD

Start date: September 6, 2021
Phase: N/A
Study type: Interventional

The aim of the research is to develop a treatment program with positive self-awareness and self-determination outcomes for adults with Attention Deficit Hyperactivity Disorder (ADHD). Current treatments are based in a characterisation of ADHD oriented on deficits impairing everyday functioning, with primary goals of symptom control and reduction. However, treatment approaches are not standardised and only evidence short-term effectiveness. This project proposes an alternative approach to understanding ADHD behaviours, supported by Self Determination Theory (SDT). Research shows SDT based treatment approaches can support engagement of intrinsic motivation and longterm integration of behavioural change. ADHD research shows individuals are impaired in some contexts but not in others and can manage well, indicating potential for ADHD neurodiverse "strengths" which could be developed and supported. Recent psychology research recommends cultivating positive psychological factors and emotions to improve mental health and wellbeing. Adults aged 18+ with a confirmed ADHD diagnosis will be invited to participate in two projects: Intensive online interviews of 1 hour will be conducted to identify, explore, and construct a theory about the factors, or "natural strengths" in lived experience of ADHD that help individuals to overcome everyday impairments. These factors will be incorporated into a pilot feasibility study of an SDT based 12-week treatment programme focusing on understanding the lived experience of ADHD and building on these strengths. The treatment will be designed for individual participants and delivered online. This study will have two sets of participants: one group will go directly to treatment, the other will go on a 12-week waiting list to create a comparison group. The second group will then be offered the 12-week treatment. Measures of experience of the participants will be looking for the feasibility, acceptability and efficacy of this treatment, as well as indicators of symptom improvement, and changes in self-awareness and self-regulation skills.

NCT ID: NCT04816175 Completed - Microcephaly Clinical Trials

Intensive Therapy for Children With Microcephaly, Hyperkinetic Movements, or Global Developmental Delay

Start date: April 30, 2019
Phase: N/A
Study type: Interventional

This trial will consist of a clinical series of up to 50 children with Global Developmental Delay and concomitant microcephaly or hyperkinetic movements. All children will be assessed for psychomotor function using standardized assessments, goal specific assessments, with the potential addition of neuroimaging assessment, prior to and after receiving an intensive burst of neuromotor therapy. The interventional effects will be explored by comparing the pre and post interventional assessments and neuroimaging.

NCT ID: NCT04786990 Completed - Clinical trials for Attention-Deficit/Hyperactivity Disorder (ADHD)

Open-Label Study of SPN-812 Administered With Psychostimulants in Children and Adolescents With ADHD

ADHD
Start date: July 27, 2021
Phase: Phase 4
Study type: Interventional

This open label, flexible-dose study evaluating the safety and efficacy of SPN-812 administered with psychostimulants in children and adolescents (6 to 17 years of age) with Attention-Deficit/Hyperactivity Disorder (ADHD).

NCT ID: NCT04786730 Completed - Clinical trials for Attention-deficit Hyperactivity Disorder

A Trial to Assess the Pharmacokinetics, Safety, and Tolerability of Centanafadine Capsules in Pediatric Subjects With Attention-deficit Hyperactivity Disorder

Start date: March 9, 2021
Phase: Phase 1
Study type: Interventional

This is a phase 1b, multicenter, open-label, multiple-dose trial in pediatric subjects (4 - 12 years of age, inclusive) with a confirmed diagnosis of ADHD.

NCT ID: NCT04707040 Completed - Clinical trials for Attention Deficit Hyperactivity Disorder

Neurocognitive Exercise Program for Children With Attention Deficit and Hyperactivity Disorder

Start date: January 8, 2018
Phase: N/A
Study type: Interventional

The effects of Neurocognitive Exercise Program (NEP) on ADHD symptoms and executive functions in children with Attention Deficit and Hyperactivity Disorder (ADHD) will be investigated using The Conners parent rating scale-revised short (CPRS-RS), Stroop Test, Wisconsin test and Y-Balance test.

NCT ID: NCT04671082 Completed - Acute Pain Clinical Trials

Efficacy and Safety of Tolperisone in Subjects With Pain Due to Acute Back Muscle Spasm

RESUME-1
Start date: December 15, 2020
Phase: Phase 3
Study type: Interventional

This is a double-blind, randomized, placebo-controlled, multicenter study of the efficacy and safety of tolperisone (a non-opioid) or placebo administered in subjects with pain due to acute back muscle spasm.

NCT ID: NCT04577417 Completed - Clinical trials for Attention Deficit Hyperactivity Disorder

Stimulant Medication Effects on Auditory Sensitivity in Teens With ADHD

Start date: September 13, 2020
Phase:
Study type: Observational

The aims of this study are to evaluate auditory sensitivity in teenagers with ADHD using acoustic reflex thresholds (ART) and to examine the effects of ADHD stimulant medication on ART.

NCT ID: NCT04569357 Completed - Clinical trials for Attention Deficit Hyperactivity Disorder

Clinical Trial of Efficacy and Safety of Prospecta in the Treatment of Attention Deficit/Hyperactivity Disorder in Children

Start date: November 20, 2020
Phase: Phase 3
Study type: Interventional

Purpose of the study: • evaluate the efficacy and safety of Prospecta in the treatment of attention deficit/hyperactivity disorder in children.

NCT ID: NCT04494230 Completed - Clinical trials for Attention Deficit Hyperactivity Disorder

Motor Proficiency in School Age ADHD: Contribution of Different Comorbidities

Start date: October 1, 2018
Phase:
Study type: Observational [Patient Registry]

In this study, aged 6-10 years, male, right hand dominant, diagnosed with ADHD, accepting to take part in the study and applying to the Child and Adolescent Psychiatry Department between October 1, 2018 - October 1, 2019 were included in the research group.As for the control group, boys between 6-10 years of age with no mental symptoms described by their teachers or parents and showing healthy development were selected by convenience sampling method and snow ball method. Height and weight measurements of all the children participated in the study were performed. The sociodemographic data form prepared by the researchers was completed by both the research and the control group families. In the sample, the Corners' Parent Scale- Revised Short Form (CPS-R:SF) was used to evaluate the severity of ADHD symptoms.The hand preferences of all participants in the research and control groups were evaluated with Edinburgh Handedness Inventory.Motor skills were evaluated with the 2nd Version of Bruininsky-Oseretsky Motor Competence Test (BOT-2).Hand skills were evaluated with the 9-Hole Peg Test.Visual perception skills were evaluated with 3rd Version of Visual Perception Test without Motor Ability (MVPT-3). Pediatric Quality of Life Inventory Parent Form were filled by the parents of children in the research and control groups for quality of life. In the study, there are five groups: ADHD, ADHD + Specific learning disorders, ADHD + Oppositional defiant disorder, ADHD + Anxiety Disorder and children with typical development group.

NCT ID: NCT04467658 Completed - Clinical trials for Attention Deficit Hyperactivity Disorder

Neurophysiological Marker of ADHD in Children

Start date: August 8, 2018
Phase:
Study type: Observational

This study investigated quantitative electroencephalography (QEEG) subtypes as auxiliary tools to assess Attention Deficit Hyperactivity Disorder (ADHD). Patient assessed using the Korean version of the Diagnostic Interview Schedule for Children Version IV and were assigned to one of three groups: ADHD, ADHD-Not Otherwise specified (NOS), and Neurotypical (NT). The investigators measure absolute and relative EEG power in 19 channels and conducted an auditory continuous performance test. The investigators analyzed QEEG according to the frequency range: delta (1-4 Hz), theta (4-8 Hz), slow alpha (8-10 Hz), fast alpha (10-13.5 Hz), and beta (13.5-30 Hz). The subjects were then grouped by Ward's method of cluster analysis using the squared Euclidian distance to measure dissimilarities.