Hyperkalemia Clinical Trial
— SZCOfficial title:
Effect of Sodium Zirconium Cyclosilicate on Hyperkalemia After Parathyroidectomy in Secondary Hyperparathyroidism Patients With Maintenance Hemodialysis
Verified date | April 2022 |
Source | Guangdong Provincial People's Hospital |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
Sodium zirconium cyclosilicate (SZC) has been demonstrated for its serum potassium-lowering efficacy and safety in hyperkalemia hemodialysis patients. However, the effects of SZC during the perioperative period remained unknown. This experiment aimed to determine whether using SZC would impact the serum potassium levels in patients with maintenance hemodialysis after parathyroidectomy (PTX).
Status | Completed |
Enrollment | 62 |
Est. completion date | December 2021 |
Est. primary completion date | December 2021 |
Accepts healthy volunteers | No |
Gender | All |
Age group | N/A and older |
Eligibility | Inclusion Criteria: - Secondary Hyperparathyroidism (SHPT) is a common and severe manifestation of chronic kidney disease (CKD), especially in end-stage renal disease (ESRD) patients. ESRD MHD with SHPT patients were recruited into this study Exclusion Criteria: - Patients with severe cardiovascular disease who cannot tolerate general anesthesia surgery were not included in this study. |
Country | Name | City | State |
---|---|---|---|
n/a |
Lead Sponsor | Collaborator |
---|---|
Guangdong Provincial People's Hospital |
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Other | Change of parathyroid hormone | Laboratory chemistry measurement | Parathyroid hormone were checked 24h before surgery and on the first day after surgery | |
Primary | Change of serum potassium levels | Laboratory chemistry measurement | Serum potassium levels were checked at three time points, which were t0 (6 am on the day of surgery), t1 (immediate after surgery), and t2 (9 pm on the day of surgery), respectively. | |
Secondary | Change of serum calcium levels | Laboratory chemistry measurement | Serum calcium levels were checked at three time points, which were t0 (6 am on the day of surgery), t1 (immediate after surgery), and t2 (9 pm on the day of surgery), respectively. |
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