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An Open-Label, Multiple Dose Study to Evaluate the Pharmacology, Safety, and Tolerability of Patiromer in Participants on Hemodialysis

Hyperkalemia Clinical Trial

Official title:
An Open-Label, Multiple Dose Study to Evaluate the Pharmacology, Safety, and Tolerability of Patiromer in Hemodialysis Patients

Clinical Trial Summary

This study assessed the pharmacodynamic effects of patiromer on serum potassium in participants on hemodialysis.

Clinical Trial Description

The initial intent was to enroll 12-24 adult male and female participants on hemodialysis into the study. Due to significant recruitment challenges, the study was discontinued after six participants were enrolled in the study. This was an open-label, multiple-dose, adaptive-design study in participants on hemodialysis. Eligible participants on hemodialysis were to remain in the Clinical Research Unit for 2 weeks (Day -7 to Day 8) and were required to consume a potassium, magnesium, calcium and sodium-controlled diet. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02033317
Study type Interventional
Source Vifor Pharma
Contact
Status Terminated
Phase Phase 2
Start date August 2008
Completion date December 2008
View Details
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