Intravenous Exenatide (Byetta) During Surgery

Status Completed

Clinical Trial Summary

The purpose of this project is to study if intravenous Exenatide is effective at maintaining normal blood glucose levels and preventing low blood glucose levels during surgery.

Clinical Trial Description

This is a single-center, block randomized, double-blind, placebo-controlled, dose-ranging study. Subjects will be randomized in equal proportions to one of three treatment arms: placebo of normal saline solution, 0.27 ng/kg/min (0.066 pmol/kg/min) IV Exenatide, and 0.41 ng/kg/min (0.099 pmol/kg/min) IV Exenatide. We will use a block number of 30 (please see power analysis) so that balance between each of the three groups will be maintained over the enrollment period. We will stratify the randomization scheme to ensure balance of diabetics and non-diabetics within the groups. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT00882050
Study type	Interventional
Source	Thomas Jefferson University
Contact
Status	Completed
Phase	Phase 1/Phase 2
Start date	March 2009
Completion date	April 2016

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