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NCT05619952 Clinical Trial

Postprandial Lipemia and Glycemia Following a High-Fat Meal

Hypercholesterolemia Clinical Trial

Official title:
Acute Effects of White Button and Shiitake Mushroom Powder Supplementation on Postprandial Lipemia and Glycemia Following a High-Fat Meal

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT05619952
Other study ID # 030-614292
Secondary ID
Status Completed
Phase N/A
First received
Last updated
Start date December 29, 2014
Est. completion date June 1, 2022

Study information
Verified date March 2023
Source State University of New York at Buffalo
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

The goal of this clinical trial is to determine the acute effects on postprandial lipemia and glycemia by supplementing a high-fat meal with either white button (WB) or shiitake (SH) mushroom powder in relatively healthy adults, aged 18 to 35.

Recruitment information / eligibility
Status Completed
Enrollment 16
Est. completion date June 1, 2022
Est. primary completion date July 1, 2016
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 18 Years to 35 Years
Eligibility Inclusion Criteria: - generally healthy - non-diabetic - normal to mildly hypercholesterolemic (Total Cholesterol 200-239 mg/dL and LDL-C 130-159 mg/dL) - have BMI <30 or BF% (men <25%, women <32%) - no known disease of the liver or gallbladder - no documented problems with fat metabolism - normal lipemic response to a lipid challenge - No known mushroom allergy Exclusion Criteria: - diabetic - pregnant - BMI >30 - liver disease - gallbladder disease - mushroom allergy - lipid disorder

Study Design

Related Conditions & MeSH terms

Intervention

Dietary Supplement:
• Mushroom Powder
Ground shiitake mushrooms or ground white button mushrooms

Locations
Country Name City State
n/a

Sponsors (1)
Lead Sponsor Collaborator
State University of New York at Buffalo

References & Publications (1)

Lillian A. Talal, Huipei Wang, Brian T. Wil-liams, Matthew J. Morris, Peter J. Horvath (2023) Acute Effects of White Button and Shiitake Mushroom Powder Supplementa-tion on Postprandial Lipemia and Glycemia Following a High-Fat Meal . International Journa

Outcome
Type Measure Description Time frame Safety issue
Primary Postprandial Lipemia Total cholesterol, LDL, HDL, triglycerides Baseline, up to 6 hours postprandial
Primary Postprandial Glycemia blood glucose Baseline, up to 6 hours postprandial
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