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Regeneron 1331 Kinetics Sub-Study HoFH

Hypercholesterolemia, Familial Clinical Trial

Official title:
A Kinetic Study Investigating Lipoprotein Metabolism Before and After the Administration of REGN1500, an ANGPTL3 Inhibitor, in Patients With Homozygous Familial Hypercholesterolemia. A Sub-study for Subjects Enrolled in the R1500-CL-1331 Clinical Trial

Clinical Trial Summary

To evaluate the lipoprotein kinetics of subjects enrolled in the R1500-CL-1331 clinical trial (NCT02265952) to assess the mechanism by which the evinacumab may affect lipid levels in HoFH subjects.

Clinical Trial Description

Subjects enrolled in the R1500-CL-1331 clinical trial (NCT0226595) will participate in a study visit before and after administration of the ANGPTL3 inhibitor REGN1500, evinacumab) for the evaluation of its effect on lipoprotein kinetics. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04722068
Study type Interventional
Source University of Pennsylvania
Contact
Status Completed
Phase N/A
Start date October 7, 2016
Completion date January 1, 2021
View Details
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