Hyperalgesia Clinical Trial
Official title:
The Effect of Gabapentin Pretreatment on Hyperalgesia in Elderly Patients Undergoing Staged Bilateral Cataract Operations
To evaluate the effect of oral gabapentin premedication on hyperalgesia in elderly patients undergoing staged bilateral cataract operations under monitored anesthesia care
It has been reported that patients with bilateral cataract complained more pain and discomfort during the second consecutive eye surgery compared to the first eye surgery. Gabapentin is an anticonvulsant drug, which has been extended the use to perioperative analgesia, and anxiolysis. Therefore, the investigators conducted this randomized, controlled study to evaluate the effects of gabapentin premedication on patients' subjective sensations, including intraoperative anxiety, perceptions of pain, and light sensitivity, in the second cataract operations. ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT01301079 -
Evaluation of the Effect of Ketamine on Remifentanil-induced Hyperalgesia
|
Phase 3 | |
Completed |
NCT00833755 -
Effect of Ketamine on Opioid-Induced Hyperalgesia
|
N/A | |
Completed |
NCT00279032 -
GW406381 In Patients With Peripheral Nerve Injury
|
Phase 1 | |
Completed |
NCT03793790 -
The Role of Learning in Nocebo Hyperalgesia
|
N/A | |
Completed |
NCT03985995 -
Pain Response to Cannabidiol in Induced Acute Nociceptive Pain, Allodynia and Hyperalgesia By Using a Model Mimicking Acute Pain in Healthy Adults
|
N/A | |
Completed |
NCT04199858 -
Electrophysiological Correlates of Nocebo Effects on Pain
|
N/A | |
Completed |
NCT02938455 -
DNA Methylation and Perioperative Pain Treatment
|
||
Not yet recruiting |
NCT02934763 -
Opioid Induced Hyperalgesia (OIH) Modulation With Propranolol
|
Phase 4 | |
Completed |
NCT02653703 -
L-menthol as a Topical Counter-irritant to TRPA1-induced Neurogenic Inflammation and Pain
|
N/A | |
Completed |
NCT02253966 -
Preoperative Intraarticular Injection of Methylprednisolone in Patients Scheduled for Total Knee-arthroplasty
|
Phase 2 | |
Terminated |
NCT01615510 -
Evaluation of the Antihyperalgesic Effect of Tapentadol in Two Human Experimental Models
|
Phase 1 | |
Completed |
NCT01702389 -
Opioid-induced Hyperalgesia After Remifentanil Infusion
|
Phase 4 | |
Completed |
NCT00218374 -
Dextromethorphan, Gabapentin, and Oxycodone to Treat Opioid-Induced Hyperalgesia
|
N/A | |
Completed |
NCT00387413 -
A Study Of GSK189254 And Duloxetine In The Electrical Hyperalgesia Model Of Healthy Volunteers
|
Phase 1 | |
Completed |
NCT04197154 -
Pain-related Fear as a Facilitator of Nocebo Hyperalgesia
|
N/A | |
Completed |
NCT02976337 -
Effect of High-dose Naloxone Following Third Molar Extraction
|
Phase 2 | |
Completed |
NCT03354624 -
Cortical Neuroplasticity by Muscle Pain of Pain-induced Plasticity
|
N/A | |
Completed |
NCT02596360 -
Dextromethorphan Effect on Central Sensitization to Pain in Healthy Volunteers
|
Phase 1 | |
Recruiting |
NCT01480765 -
Preventing Pain After Heart Surgery
|
Phase 4 | |
Recruiting |
NCT01015482 -
The Effect of High-dose Remifentanil on Established Sunburn-induced Hyperalgesia in Human Volunteers (HighDose RemiSun)
|
Phase 4 |