Clinical Trials Logo

Clinical Trial Summary

This multicenter study intends to combine retrospective analysis and prospective registry to evaluate the success rate and safety of adrenal venous sampling (AVS) via antecubital and femoral approach for patients with primary aldosteronism. The consistency of AVS with pathological results and clinical outcomes, the factors affecting the success of AVS, and the optimal population for AVS will be aslo analyzed in this study.


Clinical Trial Description

Primary aldosteronism (PA) is one of the most common causes of secondary hypertension, and its most common subtypes are aldosterone-producing adenoma and idiopathic hyperaldosteronism, which account for 95% to 98% of PA. Subtype diagnosis is crucial for the treatment of primary aldosteronism, which conducts the appropriate treatment strategy. Currently, adrenal venous sampling (AVS) serves as the gold standard for subtyping of PA. How to improve the success rate of AVS has been a hot topic in the field of primary aldosteronism. This multicenter registry study intends to combine retrospective analysis and prospective registry to evaluate the success rate and safety of AVS via antecubital and femoral approach for patients with primary aldosteronism. The consistency of AVS with pathological results and clinical outcomes, the factors affecting the success of AVS, and the optimal population for AVS will be also analyzed in this study. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT06192238
Study type Observational [Patient Registry]
Source Chinese Academy of Medical Sciences, Fuwai Hospital
Contact Xiongjing Jiang, MD
Phone 86-010-88322387
Email jxj103@hotmail.com
Status Not yet recruiting
Phase
Start date January 1, 2024
Completion date December 30, 2026

See also
  Status Clinical Trial Phase
Recruiting NCT06008184 - Real-time Monitoring of Cortisol - Comparison of Cortisol Levels in Four Biological Fluids
Recruiting NCT02945904 - IS Metomidate PET-CT Superior to Adrenal Venous Sampling in Predicting Outcome From Adrenalectomy in Patients With Primary Hyperaldosteronism
Completed NCT01431326 - Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care
Not yet recruiting NCT00553722 - Does Aldosterone Cause Hypertension by a Non-Renal Mechanism? Phase 4
Completed NCT01234220 - Adrenal Vein Sampling International Study (AVIS Study) N/A
Completed NCT00001176 - Effects of Salt Intake on the Nervous Systems of Patients With Salt-Sensitive High Blood Pressure N/A
Active, not recruiting NCT04605549 - A Study of CIN-107 in Adults With Primary Aldosteronism Phase 2
Not yet recruiting NCT03414918 - Macrolides for KCNJ5 - Mutated Aldosterone-Producing Adenoma (MAPA) N/A
Not yet recruiting NCT06246357 - Evaluating the Functional Status of the Adrenal Glands With [68Ga]Ga-PentixaFor in Hyperaldosteronism and Hypercortisolism Phase 2
Completed NCT02751021 - Sleep Apnea Diagnosis Using a Novel Pacemaker Algorithm and Link With Aldosterone Plasma Level in Patients Presenting With Diastolic Dysfunction N/A
Recruiting NCT02832388 - Primary Aldosteronism in Western Norway
Completed NCT00004354 - Study of Prevalence and Clinical Phenotype in Patients With Glucocorticoid-Remediable Aldosteronism N/A
Completed NCT01096654 - SPARTACUS: Subtyping Primary Aldosteronism: a Randomized Trial Comparing Adrenal Vein Sampling and Computed Tomography Scan. Phase 3
Completed NCT00155064 - Kallikrein-kinin (KKS) and Renin-angiotensin-aldosterone System (RAAS) in Primary Aldosteronism Phase 4
Recruiting NCT03778645 - Adrenal Venous Sampling Via an Antecubital Approach
Recruiting NCT04328181 - Comparison of Imaging Quality Between Spectral Photon Counting Computed Tomography (SPCCT) and Dual Energy Computed Tomography (DECT) N/A
Active, not recruiting NCT02030587 - Laparoscopic Adrenalectomy Versus Radiofrequency Ablation N/A
Completed NCT01897727 - Etiology of Sleep Apnea-related Hyperaldosteronism - BP Treatment N/A
Recruiting NCT00407784 - Diagnostic Properties of Aldosterone-Renin Ratio in Primary Aldosteronism Among Hypertensives. N/A
Recruiting NCT00451672 - The Therapeutic Effect of Bromocriptin in Patients With Primary Aldosteronism Phase 4