Transversus Abdominis Plane Block in Pediatrics: Volume or Concentration ? — TAP Bloc  

Hydrocele Clinical Trial

Official title: Volume or Concentration for the Transverse Abdominal Plane Block in Children Aged 1-5 Years: Analgesic Effects and Safety

Status Recruiting

Clinical Trial Summary

The transversus abdominis plane (TAP) block provide a local anesthesia drug diffusion between the transverse abdominis muscle and the internal oblique muscle. TAP block reaches the anterior rami of spinal nerves from T7 to L1 involved in the innervation of homolateral abdominal wall. The transversus abdominis plane block has shown promise for perioperative analgesia, but data on the optimal dose regimen are limited.Following previous research of optimal dose of local anesthesic solution, the investigators aim to evaluate if a "volume effect" would lead to a better diffusion of the local anesthesic solution to the overall nervous roots. The local anesthesia drug choosen is levobupivacaine with a unique posology of 0,4 mg/kg (either 0,2 ml/kg of 0,2% levobupivacaine for "small volume" group or 0,4 ml/kg of 0,1% levobupivacaine for "high volume" group).With the same dose of levobupivacaine, this study aims to assess the impact of volume effect on analgesia efficiency as well as the security as after ultrasound TAP block on one to five years' old children who undergo a peritoneal-vaginal duct surgery.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Pharmacokinetics Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Subject)

Related Conditions & MeSH terms

• Cord Kyst
• Hydrocele
• Inguinal or Ovarian Hernia
• Local Analgesia Block
• One to Five Years

• NCT number: NCT02064088
• Study type: Interventional
• Source: University Hospital, Montpellier
• Contact: Chrystelle CS SOLA, MD
• Phone: +33 665849166
• Email: c-sola@chu-montpellier.fr
• Status: Recruiting
• Phase: N/A
• Start date: November 2013
• Completion date: November 2015