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Safety and Tolerability of WVE-120101 in Patients With Huntington's Disease — PRECISION-HD1  

Huntington's Disease Clinical Trial

Official title:
A Multicenter, Randomized, Double-blind, Placebo-controlled, Phase 1b/2a Study of WVE-120101 Administered Intrathecally in Patients With Huntington's Disease

Clinical Trial Summary

PRECISION-HD1 is a Phase 1b/2a multicenter, randomized, double-blind, placebo-controlled study to evaluate the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of single and multiple doses of WVE-120101 in adult patients with early manifest Huntington's disease (HD) who carry a targeted single nucleotide polymorphism (SNP) rs362307 (SNP1).

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03225833
Study type Interventional
Source Wave Life Sciences Ltd.
Contact
Status Terminated
Phase Phase 1/Phase 2
Start date July 17, 2017
Completion date May 11, 2021
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