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Clinical Trial Summary

To determine if memantine in doses of 10 mg BID affects memory, cognition, and behavior in patients with Huntington's disease (HD).


Clinical Trial Description

Results of several published clinical trials suggest that memantine has a beneficial effect in dementing conditions, such as Alzheimer's disease; however, the effects of memantine on cognitive and behavioral function in HD are unknown. Our hypotheses are that HD patients who are administered memantine will show improved performance on psychometric tests of memory and executive functions in addition to behavior and that patients treated with memantine will show more improvement after six months than after three months of treatment. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT00652457
Study type Interventional
Source University of California, San Diego
Contact
Status Completed
Phase Phase 4
Start date November 23, 2004
Completion date October 28, 2009

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