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An Open Label Study of ANX005 in Subjects With, or at Risk for, Manifest Huntington's Disease

Huntington Disease Clinical Trial

Official title:
A Phase 2a Open Label Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Intravenous ANX005 in Subjects With, or at Risk for, Manifest Huntington's Disease

Clinical Trial Summary

This study is a multi-center, open-label study of intravenous (IV) ANX005 in subjects with, or at risk for, manifest Huntington's Disease (HD).

Clinical Trial Description

The objective of this study is to evaluate the effects of intravenous ANX005 administered for up to 22 weeks in subjects with, or at risk for, manifest Huntington's Disease. Subjects will receive induction dosing of ANX005 administered by IV infusion on Days 1 and 5 or 6, followed by maintenance dosing every 2 weeks through Week 22, with follow up visits on Weeks 24, 28, and 36. All subjects will be contacted (in clinic visit or phone call) 6 months after study completion. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04514367
Study type Interventional
Source Annexon, Inc.
Contact
Status Completed
Phase Phase 2
Start date August 17, 2020
Completion date January 28, 2022
View Details
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