Effects of Hookah (Waterpipe) Smoking on Blood Vessel Function

Hookah Smoking Clinical Trial

Official title: Effects of Hookah Smoking on Vascular Regulation: Novel Insight Into Endothelial Function

Status Terminated

Clinical Trial Summary

The purpose of this study is to assess the acute effects of Hookah (waterpipe) smoking on blood vessel function. Hookah smoking has been shown to immediately increase blood pressure and heart rate which could result in damage in the inner lining of the body's blood vessels.

Clinical Trial Description

The investigators will measure acute endothelial and vascular changes before and after a 30-minute Hookah smoking session in a controlled laboratory environment to: (1) Determine the acute effects of Hookah smoking on large-vessel endothelial vasodilator function measured by brachial artery flow mediated dilation; (2) Determine the acute effects of Hookah smoking on micro-vessel endothelial function as measured by reactive hyperemia peripheral arterial tonometry; (3) Determine the acute effects of Hookah smoking on pulse wave velocity and aortic pressure waveform measured by pulse tonometry. ;

Related Conditions & MeSH terms

• Hookah Smoking

• NCT number: NCT03616002
• Study type: Interventional
• Source: Cedars-Sinai Medical Center
• Status: Terminated
• Phase: N/A
• Start date: January 1, 2015
• Completion date: March 2020