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Clinical Trial Summary

Prospective, multicenter, Phase II trial designed to assess whether intensification of ABVD (dd-ABVD) is feasible and can improve the outcome of patients with early stage Hodgkin Lymphoma.


Clinical Trial Description

Dose-density has been shown to be an important factor for complete remission rate and longterm survival in lymphomas.

The aims of this study were to find out whether intensification of ABVD (dd-ABVD) is feasible and can improve the outcome of patients with early stage Hodgkin Lymphoma. In view of emerging data on the role of early PET in defining prognosis in Hodgkin Lymphoma patients, the percentage of FDG-PET (fluorodeoxyglucose positron emission tomography) negativity after two cycle was chosen as the parameter to evaluate dd-ABVD activity. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT02247869
Study type Interventional
Source Fondazione Italiana Linfomi ONLUS
Contact
Status Completed
Phase Phase 2
Start date February 2012
Completion date April 29, 2017

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