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NCT03487224 Clinical Trial

Neural Mechanisms of Decision Making in Hoarding Disorder

Hoarding Disorder Clinical Trial

— LOSS  

Official title:
Neural Mechanisms of Decision Making in Hoarding Disorder

Clinical Trial Details — Status: Active, not recruiting

Administrative data
NCT number NCT03487224
Other study ID # 42327
Secondary ID
Status Active, not recruiting
Phase
First received
Last updated
Start date July 8, 2018
Est. completion date May 30, 2024

Study information
Verified date April 2024
Source Stanford University
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

The purpose of this study is to understand the neural mechanisms of decision making in hoarding disorder.

Description:

Hoarding disorder is a common and disabling disorder that represents a significant public health problem. This study aims to build on current research on decision making by examining these processes in hoarding disorder.

Recruitment information / eligibility
Status Active, not recruiting
Enrollment 25
Est. completion date May 30, 2024
Est. primary completion date May 30, 2024
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 18 Years to 70 Years
Eligibility Identify inclusion criteria. Inclusion criteria for participants diagnosed with HD: 1. ages 18-70 2. primary diagnosis of hoarding disorder 3. sufficient severity of hoarding symptoms 4. stable on psychotropic medications for 1 month prior to study enrollment 5. capacity to provide informed consent 6. ability to tolerate clinical study procedures Inclusion criteria for healthy control participants: 1. ages 18-70 2. capacity to provide informed consent Identify exclusion criteria. Exclusion criteria for participants with HD: 1. psychiatric or medical conditions that make participation unsafe 2. pregnant or nursing females 3. concurrent use of any medications that might increase the risk of participation (e.g. drug interactions) 4. presence of metallic device or dental braces Exclusion criteria for healthy control participants: 1. any current or lifetime psychiatric diagnosis 2. current or past use of psychotropic medication 3. pregnant or nursing females 4. major medical or neurological problem 5. presence of metallic device or dental braces

Study Design

Related Conditions & MeSH terms

Intervention

Device:
• MRI with fMRI frequency
Functional magnetic resonance imaging or fMRI measures brain activity by detecting changes in blood flow. Participants will do cognitive tasks during fMRI.

Locations
Country Name City State
United States Stanford University Stanford California

Sponsors (1)
Lead Sponsor Collaborator
Stanford University

Country where clinical trial is conducted

United States, 

Outcome
Type Measure Description Time frame Safety issue
Primary BOLD signal BOLD signal derived from fMRI up to 90 minutes
See also
  Status Clinical Trial Phase
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Active, not recruiting NCT02306174 - Cognitive Rehabilitation and Exposure-based Class for Compulsive Hoarding N/A
Not yet recruiting NCT04811807 - Clinical Response of Impulsivity After Brain Stimulation in Parkinson's Disease
Completed NCT02584764 - Internet Supported Group Cognitive Behavior Therapy (CBT) for Hoarding Disorder (HD) N/A
Completed NCT04270825 - Group Treatment for Hoarding Disorder N/A
Active, not recruiting NCT02402647 - Cognitive Rehab and Exposure Treatment for Hoarding N/A
Enrolling by invitation NCT05254015 - Cognitive Rehabilitation and Exposure Therapy for Geriatric Hoarding N/A
Recruiting NCT04697849 - Functional and Cognitive Rehabilitation of Hoarding Disorder N/A
Recruiting NCT05237466 - Motivational Interviewing to Enhance Behavioral Change in Older Adults With Hoarding Disorder N/A
Completed NCT01451697 - Cognitive Remediation for Neuropsychological Impairment in Compulsive Hoarding Early Phase 1
Completed NCT03828461 - Hoarding Disorder Treatment With Virtual Reality N/A
Recruiting NCT04712474 - In-home Decluttering Augmentation of Group CBT for HD N/A
Completed NCT02367430 - Critical Time Intervention for Individuals With Hoarding Disorder N/A
Active, not recruiting NCT03734705 - Imaginal Exposure for Hoarding Disorder N/A
Not yet recruiting NCT03772301 - Evaluation of Hoarding Behaviour and Eating Disorders Among Holocaust Survivors and Their Descendants
Completed NCT02377986 - Augmenting Buried in Treasures Workshop (BIT) With In-home Decluttering Practice for Individuals With Hoarding Disorder N/A
Completed NCT02040805 - Comparison of Treatment for Hoarding Disorder N/A
Completed NCT04239729 - Web-based Acceptance and Commitment Therapy for Hoarding Disorder N/A
Recruiting NCT05985356 - Neuromodulation for Comorbid Hoarding Disorder and Depression N/A
Completed NCT04894851 - Contingency Management for Hoarding Disorder N/A

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