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HIV Prevention clinical trials

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NCT ID: NCT05804461 Recruiting - HIV Prevention Clinical Trials

Optimizing Pre-Exposure Prophylaxis (PrEP) Among Latino Men Who Have Sex With Men (MSM) in Puerto Rico

Start date: September 1, 2023
Phase: N/A
Study type: Interventional

To develop, assess and compare the effectiveness of a Motivational Interviewing Intervention for increasing Pre-Exposure Prophylaxis (PrEP) uptake among Latino Men Who Have Sex With Men (MSM) in Puerto Rico.

NCT ID: NCT05755204 Recruiting - HIV Prevention Clinical Trials

A Pharmacist-run PrEP Program for Women

OPTIMIZE
Start date: June 21, 2023
Phase:
Study type: Observational

The primary objective of this study is to evaluate uptake and retention of long acting cabotegravir (LA-CAB) also known as Apretude versus daily oral tenofovir disoproxil fumarate/emtricitabine (TDF/FTC) also known as Truvada for PrEP among high-risk women in metro-Orlando through week 48 (to also include reasons for lack of retention in PrEP care)

NCT ID: NCT05690815 Active, not recruiting - HIV Prevention Clinical Trials

Express Testing and Same-day Initiation of PrEP Study

Express-PrEP
Start date: January 24, 2023
Phase:
Study type: Observational

This study is an observational cohort study to measure the impact of express testing and same-day initiation of Pre-Exposure Prophylaxis (PrEP) on outcomes related to the PrEP cascade. The investigators expect that same day initiation for PrEP will improve PrEP uptake. The investigators hypothesize that baseline HIV test positivity will be higher than that of general testing for gbMSM in Ontario. This is a key indicator to determine whether this targeted approach is able to access the highest risk population.

NCT ID: NCT05644834 Recruiting - HIV Prevention Clinical Trials

Pilot Mobile Medical Unit Study for I'm Fully Empowered4Her

IFE4Her
Start date: April 18, 2023
Phase: N/A
Study type: Interventional

The overarching objective for the pilot study is to test the feasibility of using a mobile medical unit as a delivery mode combined with enhanced Pre-exposure Prophylaxis (PrEP) messaging to increase awareness of PrEP and access to PrEP medical services among women living in public housing.

NCT ID: NCT05528653 Recruiting - HIV Prevention Clinical Trials

Telehealth as a Modality to Increase the Uptake of PrEP Services in Black and Latino: "e-PrEP"

e-PrEP
Start date: July 19, 2022
Phase: Phase 4
Study type: Interventional

To evaluate if utilizing Telehealth medicine for access to HIV PrEP will engage more Black and Latino Men who have sex with Men (MSM)

NCT ID: NCT05474313 Recruiting - HIV Prevention Clinical Trials

A Study Evaluating An Integrated Pharmacy Digital Diary and Delivery Strategy to Increase PrEP Use Among MSM and TGW

PrEP-3D RCT
Start date: April 8, 2022
Phase: N/A
Study type: Interventional

The PrEP 3D randomized controlled trial (RCT) will study the effectiveness of the PrEP-3D app compared to standard of care for starting pre-exposure prophylaxis (PrEP), continuing PrEP, and adherence to PrEP.

NCT ID: NCT05420207 Not yet recruiting - HIV Prevention Clinical Trials

Implantable Long-Acting Pre-Exposure Prophylaxis For MSM

Start date: April 2024
Phase:
Study type: Observational

The long-term goal of this project is to better understand factors at the patient and physician level that can be addressed to impact uptake of long-acting, implantable PrEP (LA-PrEP) products in the future and identify the training needs of physicians. This project specifically focuses on men who have sex with men (MSM) seen in primary care settings in Texas. The main objective of this project is to examine perspectives of MSM and physicians in Texas regarding LA-PrEP, including attitudes and barriers to use and implementation by interviewing patients and physicians from the same clinical practices.

NCT ID: NCT05412433 Recruiting - HIV Prevention Clinical Trials

Clinic-based HIV Identification and Prevention Project Using Electronic Resources

CHIPPER
Start date: October 3, 2022
Phase: N/A
Study type: Interventional

Hybrid Type II effectiveness-implementation trial to investigate whether electronic medical and sexual history data collection with HIV risk categorization/scoring will increase pre-exposure prophylaxis (PrEP) uptake among cis-gender women attending routine well-woman gynecologic preventative visits.

NCT ID: NCT05365958 Completed - HIV Prevention Clinical Trials

Podcasting HIV Prevention Within African American Communities

Start date: February 11, 2022
Phase: N/A
Study type: Interventional

Given the continued impact of HIV among African Americans, there is still an urgent need to expand prevention efforts and HIV testing in African American communities. Heterosexual individuals may acquire and spread infection directly through heterosexual contact, bi-sexual sexual contact, and/or indirectly through homosexual sexual contact. Evidence-based interventions (EBIs) have been shown to increase consistent condom use, decrease sexual partners, and increase HIV testing; however, traditionally-implemented EBIs may not be accessible to communities given the resources and expertise needed to implement them. This project seeks to: 1) assess feasibility for the development of two theory- based, video podcast-delivered, HIV prevention interventions for self-identified heterosexual African American males and females; and 2) evaluate their feasibility & effectiveness (pilot). The investigators will develop the two (male and female) video podcasts that maintain the theoretical integrity of two established Centers for Disease Control evidence-based behavioral HIV prevention interventions. The assessment phase will consist of leveraging African American community stakeholders and experts in the development of the podcast content. The effectiveness phase will consist of broadcasting the podcasts for participants and evaluating psychosocial factors related to HIV prevention at 1 and 3 month follow-ups. This intervention is the first of its kind and has the potential to increase HIV protective behaviors in this hard-to-reach and medically underserved population. The resulting interventions are expected to be easily disseminated throughout the African American communities, with the potential to reduce HIV- related disparities within this population. This study will impact and advance the field by demonstrating feasibility and effectiveness for a novel mode of intervention engagement within HIV prevention science, serve as valuable preliminary data for a larger R01 trial, and foster HIV prevention awareness within the African American community.

NCT ID: NCT05338996 Completed - HIV Prevention Clinical Trials

Addressing Health Disparities in Engagement, Retention, and Utilization of PrEP Among South Florida Women of Color

Start date: October 1, 2021
Phase: N/A
Study type: Interventional

Women of color (WOC) in South Florida, the region with the highest HIV rates in the U.S., experience significant barriers to accessibility, uptake, and utilization of Pre-exposure prophylaxis (PrEP) for HIV prevention, despite FDA approval since 2012. The purpose of this study is to use a Community-Based Participatory Research (CBPR) approach to finalize, and pilot-test a multi-component evidence-based intervention to reduce health disparities in engagement, utilization, and retention in PrEP care, with the goal of improving HIV prevention outcomes for the target population of WOC in S. Florida, primarily African American, Latina, and Haitian women in 3 designated Ending the HIV Epidemic (EHE) counties: Miami-Dade, Broward, and Palm Beach counties.