HIV/AIDS Clinical Trial
— ReCharge2Official title:
Re-engagement at Discharge 2: Improving Post-hospital Outcomes for Adults With HIV in Zambia
Verified date | March 2024 |
Source | University of Maryland, Baltimore |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
Early post-discharge mortality is high among Zambians living with HIV admitted to the hospital. This may be due to missed opportunities in post-discharge care, such as inadequate follow-up and treatment. In this study the investigators will develop and pilot a new approach to post-discharge HIV care to improve care coordination and treatment adherence.
Status | Active, not recruiting |
Enrollment | 100 |
Est. completion date | July 31, 2024 |
Est. primary completion date | December 10, 2023 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years and older |
Eligibility | Inclusion Criteria: - Age 18+ years - HIV-positive - Hospitalized for at least 1 night at study site - Clinically stable and expected to be discharged according to their clinician - Objective evidence of suboptimal HIV outcome, defined as HIV viral load above the lower limit of the assay or T-cell cluster of differentiation 4 count <=200. Exclusion Criteria: - Unable to provide informed consent - No phone - Planning to reside outside of Lusaka urban district after discharge |
Country | Name | City | State |
---|---|---|---|
Zambia | Levy Mwanawasa University Teaching Hospital | Lusaka | |
Zambia | University Teaching Hospital | Lusaka |
Lead Sponsor | Collaborator |
---|---|
University of Maryland, Baltimore | University of Alabama at Birmingham, University of Maryland, College Park, University Teaching Hospital, Lusaka, Zambia |
Zambia,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Post-Discharge Visits | Proportion of discharged patients who are successfully visited after discharge. | Through three months post-discharge | |
Primary | Comprehensive Post-Discharge Visits | Proportion of discharge follow-up visits by a community health worker that are comprehensive | Through three months post-discharge | |
Primary | Post-Discharge Clinic Visits | Proportion of initial post-discharge visits to the HIV clinic that are attended by the participant's community health worker | Through three months post-discharge | |
Secondary | HIV viral load suppression | Proportion of clients with suppressed HIV viral load at 6 months post-discharge. | 6 months post-discharge | |
Secondary | Mortality | Proportion of clients alive at 6 months post-discharge. | 6 months post-discharge | |
Secondary | Retention in HIV care | Retention in HIV care after discharge defined by no gap of >28 days off antiretroviral therapy from discharge date to 6 months post-discharge date | 6 months post-discharge | |
Secondary | Antiretroviral therapy clinic visit | Antiretroviral therapy clinic visit within 1 month of discharge | 1 month post-discharge |
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