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Clinical Trial Summary

This is a 96 week study to determine if UK- 453,061 in combination with Darunavir /ritonavir and a Nucleos(t)ide Reverse Transcriptase inhibitor is as efficacious, safe and tolerable as etravirine in combination with Darunavir /ritonavir and a Nucleos(t)ide Reverse Transcriptase inhibitor in HIV-1 infected patients who have been previously treated with antiretroviral drugs and have NNRTI resistance mutations.


Clinical Trial Description

The trial was terminated on 12 April, 2012 due to lack of efficacy at the Week 24 analysis. The decision to terminate the trial was not based on any safety concerns. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT00823979
Study type Interventional
Source Pfizer
Contact
Status Terminated
Phase Phase 2
Start date March 25, 2009
Completion date October 18, 2012

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