Hip Replacement Arthroplasty Clinical Trial
Official title:
Determination of Metal Ion Levels in the Serum and Assessment of the Respective Cytokine Production of Peripheral Blood Cells in Patients With a Hard-on-hard Bearing Total Hip Replacement
The goal of the study is the analysis of metal ion serum concentrations and of the cytokine
production in the blood of patients with a conventional cementless total hip replacement. The
rationale is that a) the bearing wear releases particles respectively metal ions into the
joint and the blood which will differ in quantity and composition; b) the cytokine production
of peripheral blood mononuclear cells (PBMC) might be influenced to a varying degree by the
metal and the ceramic particles.
The patients from whom the respective samples will be analyzed are randomized in one of the
following three groups: metal-on-metal, ceramic-on-ceramic or ceramic-on-metal. A 36mm
bearing is used in all patients. In this separate study, follow-up data of the clinical and
radiographic examinations of the patients are available.
n/a
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT00542516 -
Comparison Between Two Techniques of Volemic Expansion in Hip Replacement Arthroplasty
|
Phase 4 | |
| Active, not recruiting |
NCT03505580 -
AMIStem-H Radiological Assessment
|
||
| Completed |
NCT02162121 -
Stimulating Catheter for Lumbar Plexus Block: Better Postoperative Analgesia?
|
Phase 4 | |
| Active, not recruiting |
NCT03724058 -
Fixation and Stability of the Trident® II Clusterhole HA Shells
|
N/A | |
| Recruiting |
NCT02346513 -
Serum Level of Cobalt and Chromium After Ceramic on Metal Articulation Total Hip Arthroplasty
|
N/A |