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Hip Fractures clinical trials

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NCT ID: NCT03133195 Recruiting - Clinical trials for Unstable Intertrochanteric Fracture

The Effect of Teriparatide on Bone Union in Unstable Intertrochanteric Fracture Patients Treated With PFNA

Start date: May 17, 2017
Phase: Phase 3
Study type: Interventional

Phase III, prospective, randomized, parallel, double blind, placebo-controlled study to determine whether Teriparatide can accelerate bone healing in unstable intertrochanteric fracture patients treated with Proximal Femoral Nail Antirotation (PFNA) assessed by radiographic and clinical outcomes.

NCT ID: NCT03116490 Recruiting - Clinical trials for Postoperative Complications

The Effects of Anesthesia Type on the Prognosis of Hip Fracture Surgery on Elderly Patients

Start date: January 16, 2017
Phase:
Study type: Observational

The aim of this study is to figure out whether anesthesia type have an influence on the prognosis of hip fracture surgery.30-day mortality and morbidity after the surgery are our main observational index,and according to literature and our experience,regional anesthesia may have a better prognosis after hip fracture surgery compared with general anesthesia.

NCT ID: NCT03092466 Recruiting - Hip Fractures Clinical Trials

Early Femoral Block in Elderly With Hip Fracture

Start date: February 26, 2017
Phase: N/A
Study type: Interventional

Assess if the addition of an early femoral nerve block (performed within 2 hours from the admission in emergency department through a femoral nerve catheter) in the elderly patients (> 70 years) with hip fracture, reduces the incidence of postoperative delirium assessed by CAM 3Ds test, compared to the traditional systemic pain therapy.

NCT ID: NCT03063892 Recruiting - Hip Fractures Clinical Trials

Effect of Tranexamic Acid (TXA) on Reduction of Postoperative Blood Transfusion

Start date: August 30, 2017
Phase: Phase 4
Study type: Interventional

Tranexamic Acid (TXA) is an antifibrolytic medication used in total hip and knee arthroplasty to reduce the need for intraoperative and postoperative blood transfusions. Limited research is available on its use in hip fracture patients. We hypothesize that the use of TXA preoperatively, perioperatively, and postoperatively will decrease blood loss and need for blood transfusion postoperatively.

NCT ID: NCT02996383 Recruiting - Hip Fractures Clinical Trials

Fixation Versus Arthroplasty for Undisplaced Intracapsular Fractures

Start date: May 2016
Phase: N/A
Study type: Interventional

In England each year over 70,000 people fracture their hip. Most of these patients are elderly females with the fracture occurring after a simple trip or stumble. Approximately half of these fractures are classified from their relationship to the hip joint capsule as intracapsular. These fractures are subdivided into those that are displaced and those that are undisplaced. The majority of displaced fractures are treated with a replacement arthroplasty. Current treatment for the undisplaced fractures is generally by internal fixation of the fracture using screws and a plate, although some centres prefer replacement arthroplasty. A recent randomised study on patients from Norway with undisplaced intracapsular fractures treated with either internal fixation or arthroplasty has just reported reduced complications and re-operations for those patients treated with an arthroplasty. In addition functional results were marginally better for those patients treated with an arthroplasty. Current practice in the UK is generally to treat these fractures by internal fixation. This study aims to see if replacement arthroplasty can indeed lead to the advantages suggested from the Norwegian study. Patients who satisfy the inclusion criteria and are willing to participate will be randomised to receive either reduction and internal fixation of the fracture with a screw and plate device or alternatively replacement of their femoral head with an artificial hip replacement (hemiarthroplasty). After surgery patients will receive the same treatment as normal and be discharge home when able, with follow-up review in the hip fracture clinic. Subsequent follow-up for the research project is by phone calls from a research nurse who is blinded to the type of treatment that the patient has received. There will be no additional investigations or out-patient follow-up visits for these patients in comparison to normal treatment protocols. Results of the study will ultimately be published in a medical journal.

NCT ID: NCT02968589 Recruiting - Hip Fractures Clinical Trials

@ctiveHip Tele-rehabilitation System

@ctiveHip
Start date: January 2017
Phase: N/A
Study type: Interventional

The purpose of this study is to determine if the @ctivehip tele-rehabilitation system improves the functional level and quality of life of hip fracture patients and reduce the caregiver burden.

NCT ID: NCT02788994 Recruiting - Clinical trials for Unilateral Unstable Hip

Stabilization of Fresh Unilateral Unstable Pertrochanteric Hip Fracture

PET
Start date: June 2016
Phase: N/A
Study type: Interventional

This is a preliminary study to establish the issues and potential of the investigators proposed project, which involves recruitment of patients with and without dementia, who have been admitted to hospital following hip fractures. The study will be evaluating the result of treatment of unstable pertrochanteric hip fractures focusing on how soon mobility is restored leading to their independence. These patients would require surgical fixation (not replacement) of their hip fractures. The study will evaluate two methods of fixation of hip fractures treated with either a pin (nail) which is inserted within the cavity of the thigh bone or a hip screw with a plate which is applied on the outer aspect of the thigh bone. The data collected from this study will provide information on whether one method of fixation is better than the other.

NCT ID: NCT02738073 Recruiting - Hip Fracture Clinical Trials

Effects of Tranexamic Acid on Blood Loss and Transfusion Requirement Following Hip Fracture

Start date: n/a
Phase: N/A
Study type: Interventional

Tranexamic acid (TA) inhibits fibrinolysis by binding to lysine binding-sites of plasminogen to fibrin. Fibrinolysis is stimulated by surgical trauma, and the administration of TA has been shown effective in decreasing blood loss both intra-operatively and in the immediate post-operative period in elective hip and knee arthroplasty patients. Both the timing and dosing of TA has been investigated in these patients. Subsequent blood transfusion rate has also been shown to decrease as result of TA administration. Despite the support for TA utilization that exists in the arthroplasty literature, the data is scarce regarding its administration during surgical treatment of hip fractures. This is patient population who is at high risk for transfusion due to symptomatic post-operative anemia. This study aims to investigate whether TA's advantageous effects in the arthroplasty patient population can be extrapolated to the more unstable, heterogeneous hip fracture patient population. If the study is able to show a difference in blood loss and transfusion requirement, the long term implications of this with regards to cost and mortality can be significant.

NCT ID: NCT02672696 Recruiting - Femoral Fractures Clinical Trials

Interest of Navigation for the Treatment of Pertrochanteric Fractures With the Gamma 3 Nail

INOPEG
Start date: May 2015
Phase: N/A
Study type: Interventional

The aim of the study is to compare Tip-Apex Distance values in two groups of patients after intramedullary nailing of proximal femur. The first group of patients is operated with the help of a 3D reconstruction device connected to the standard fluoroscopy allowing the surgeon to visualize directly the exact position of the tip of the trans-cervical screw while the second group (which is the reference-group) is operated with the help of fluoroscopy alone.

NCT ID: NCT02635763 Recruiting - Hip Fracture Clinical Trials

Peripheral Nerve Blocks in Elderly Patients With Hip Fracture

Start date: October 2015
Phase: N/A
Study type: Interventional

As the population ages, the frequency of surgery is increasing proportionally, bringing with it the challenge of managing older patients with frequent comorbid diseases and an increased risk of complications. Poor postoperative quality of recovery may result in patient and family suffering, a prolonged hospital stay, and a greater demand on health care resources.The purpose of this study was to evaluate the ultrasound guided percutaneous femoral nerve+lateral cutaneous nerve versus lumbar plexus+sacral plexus nerve block composite laryngeal mask anesthesia in elderly hip fracture surgery, the application of assessing their impact on the postoperative recovery quality.