Stem Cells Predicting Orthopedic Outcomes

Status Completed

Clinical Trial Summary

This is a pilot study to provide preliminary data of the association between bone mineral denity adjacent to acetabular implants, as measured by quanitative computed tomography (QCT), at least 2 years post Total Hip Arthoplasty (THA) surgery with Mesechymal stem cell assays, obtained at time of surgery, and to begin to evaluate if stem cells can predict orthopaedic surgical outcomes.

Clinical Trial Description

Subjects who have undergone a THA and who previously consented to "Stem Cell Quality Assays: Correlation with Aging/Health" study which used excess bone marrow and blood samples to complete stem cell assay labs will be invited back at least 2 years post THA to complete bilateral hip x-rays, if not already completed as part of routine medical follow up plus a QCT bone density testing and to complete a questionnaire regarding smoking, alcohol and exercise history along with recording BMIs. This ability to identify older individuals with compromised stem cell function could offer opportunities to develop and test new preventative and therapeutic strategies to improve outcomes. ;

Study Design

Related Conditions & MeSH terms

Hip Arthroplasty

Clinical Trial Details

NCT number	NCT01366911
Study type	Observational
Source	University of Nebraska
Contact
Status	Completed
Phase
Start date	April 22, 2011
Completion date	January 10, 2014

View Details

See also
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