High Risk Pregnancy Clinical Trial
Official title:
Frequency of Performing Umbilical Artery Doppler in the Third Trimester in High Risk Pregnancy A Randomized Controlled Trial
The aim of the current study was to produce a high quality evidence on the best frequency of performing umbilical artery Doppler for high risk pregnant women in the third trimester.
Nowadays, high risk pregnancy forms a significant increasing proportion of any pregnant
population, according to some authors up to 50% of all pregnancies would have the label of
high risk pregnancies.
At present, it is recommended that high risk pregnancies, thought to be at risk of placental
insufficiency should be monitored with Doppler studies of the umbilical artery. Doppler
assessment of the placental circulation plays an important role in screening for impaired
placentation and its complications of intrauterine growth restriction.
The purpose of umbilical artery Doppler surveillance is to predict fetal academia thereby
allowing timely delivery prior to irreversible end-organ damage and intrauterine fetal death.
According to a Cochrane Pregnancy and Childbirth Group's systematic review and meta-analysis,
in which Published and unpublished randomised and quasi-randomised trials evaluating the
effects of one or more described antenatal fetal surveillance regimens were searched, the
optimal frequency of umbilical artery Doppler surveillance is unclear.
Our randomized controlled study was conducted on patients with high risk pregnancies at their
third trimester who attended Ain Shams University Maternity Hospital. A total of 292 high
risk pregnant women fulfilling the inclusion criteria were selected by random sampling and
divided between two groups with 146 patients in each group. Group I underwent Doppler every
other week and Group II underwent Doppler once weekly.
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