Herpes Zoster Clinical Trial
Official title:
Efficacy of Pregabalin for the Treatment of Acute Herpetic Neuralgia and for the Prevention of Post Herpetic Neuralgia- a Randomized Controlled Trial
All eligible Herpes Zoster patients will be randomized into two groups. Group 1 will be the treatment group receiving Pregabalin 75 mg twice daily for 4 weeks in addition to other routine treatment. Whereas, group 2 will be the control group receiving all routine treatment similar to group 1 except Pregabalin. Instead control group will receive Placebo.
This study wants to see the role of Pregabalin in acute herpetic neuralgia pain reduction and
for the prevention of post herpetic neuralgia incidence as compared to placebo group. For
this purpose, all eligible Herpes Zoster patients will be randomized into two groups (41
patients in each group i.e.82 total patients). Group 1 will be the treatment group receiving
Pregabalin 75 mg twice daily for 4 weeks in addition to other routine treatment. Whereas,
group 2 will be the control group receiving all routine treatment similar to group 1 except
Pregabalin. Instead of pregabalin, control group will receive Placebo. The pain will be
evaluated in all patients in each follow visits (weekly follow up for 4 weeks then monthly
follow up for next three months). If it is difficult for the patient to present physically,
telephonic follow up will be done to find the pain score in the required time. Also, DLQI
(Dermatological life quality index) will be assessed at the first and last visit of the
patient.
At the end, pain score will be compared between the two groups.
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