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Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT00759005
Other study ID # NIDD
Secondary ID
Status Completed
Phase N/A
First received September 23, 2008
Last updated September 23, 2008
Start date March 2007
Est. completion date September 2008

Study information

Verified date September 2008
Source National Institute on Drug Dependence, China
Contact n/a
Is FDA regulated No
Health authority China: Peking University Research Ethics Committee
Study type Interventional

Clinical Trial Summary

The purpose of this study is to determine whether cortisol and propranolol are effective in the modulation of stress induced heroin-related retrieval enhancement.


Recruitment information / eligibility

Status Completed
Enrollment 0
Est. completion date September 2008
Est. primary completion date June 2008
Accepts healthy volunteers No
Gender Male
Age group 20 Years to 40 Years
Eligibility Inclusion Criteria:

- Participants had to have met DSM-IV criteria for heroin dependence prior to abstinence.

Exclusion Criteria:

- current use of any medications; current DSM-IV diagnosis of any affective, anxiety, or psychotic disorder; current dependence on any substance besides heroin and nicotine (based on DSM-IV criteria); or risk factors for untoward side effects from propranolol and cortisol (i.e., irregular heartbeats, history of cardiogenic shock, history of severe heart failure, asthma, fungal Infections, hyperlipidemia, history of hypertension, or abnormal ECG or other laboratory findings).

Study Design

N/A


Related Conditions & MeSH terms


Intervention

Drug:
propranolol and cortisol


Locations

Country Name City State
China National Institute on Drug Dependence Beijing Beijing

Sponsors (1)

Lead Sponsor Collaborator
National Institute on Drug Dependence, China

Country where clinical trial is conducted

China, 

Outcome

Type Measure Description Time frame Safety issue
Primary Glucocorticoids enhanced heroin-related memory retrieval in abstained heroin addicts Yes
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